IL33 (MIM 608678) is a member of the IL1 (see MIM 147760) family that potently drives production of T helper-2 (Th2)-associated cytokines (e.g., IL4\; MIM 147780). IL33 is a ligand for IL33R (IL1RL1\; MIM 601203), an IL1 family receptor that is selectively expressed on Th2 cells and mast cells (summary by Yagami et al., 2010 [PubMed 20926795]).[supplied by OMIM, Jan 2011].
custom-made
IL33
宿主: 小鼠
宿主: Cell-free protein synthesis (CFPS)
Recombinant
approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC).
SDS, WB, ELISA
custom-made
IL33
宿主: 人
宿主: Cell-free protein synthesis (CFPS)
Recombinant
approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC).
SDS, WB, ELISA
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Deng, Wang, Shan, Chen, Zhou, Zhao, Xia: "Tristetraprolin inhibits gastric cancer progression through suppression of IL-33." in: Scientific reports, Vol. 6, pp. 24505, (2016) (PubMed).
Zhang, Xie, Chen, Mai, Wang, Zhu, Zhu: "Altered serum levels of IL-33 in patients with advanced systolic chronic heart failure: correlation with oxidative stress." in: Journal of translational medicine, Vol. 10, pp. 120, (2012) (PubMed).
Suzukawa, Nagase, Ogahara, Han, Tashimo, Shibui, Koketsu, Nakae, Yamaguchi, Ohta: "Leptin enhances survival and induces migration, degranulation, and cytokine synthesis of human basophils." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 186, Issue 9, pp. 5254-60, (2011) (PubMed).
Suzukawa, Iikura, Koketsu, Nagase, Tamura, Komiya, Nakae, Matsushima, Ohta, Yamamoto, Yamaguchi: "An IL-1 cytokine member, IL-33, induces human basophil activation via its ST2 receptor." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 181, Issue 9, pp. 5981-9, (2008) (PubMed).
Suzukawa, Koketsu, Iikura, Nakae, Matsumoto, Nagase, Saito, Matsushima, Ohta, Yamamoto, Yamaguchi: "Interleukin-33 enhances adhesion, CD11b expression and survival in human eosinophils." in: Laboratory investigation; a journal of technical methods and pathology, Vol. 88, Issue 11, pp. 1245-53, (2008) (PubMed).
Iikura, Suto, Kajiwara, Oboki, Ohno, Okayama, Saito, Galli, Nakae: "IL-33 can promote survival, adhesion and cytokine production in human mast cells." in: Laboratory investigation; a journal of technical methods and pathology, Vol. 87, Issue 10, pp. 971-8, (2007) (PubMed).