IL-10RA 抗体
(Interleukin 10 Receptor, alpha (IL10RA))
The protein encoded by this gene is a receptor for interleukin 10. This protein is structurally related to interferon receptors. It has been shown to mediate the immunosuppressive signal of interleukin 10, and thus inhibits the synthesis of proinflammatory cytokines. This receptor is reported to promote survival of progenitor myeloid cells through the insulin receptor substrate-2/PI 3-kinase/AKT pathway. Activation of this receptor leads to tyrosine phosphorylation of JAK1 and TYK2 kinases. Two transcript variants, one protein-coding and the other not protein-coding, have been found for this gene. [provided by RefSeq, Jan 2009].
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Latest Publications for our IL-10RA 抗体
: "Functional analysis of bovine interleukin-10 receptor alpha in response to Mycobacterium avium subsp. paratuberculosis lysate using CRISPR/Cas9." in: BMC genetics, Vol. 21, Issue 1, pp. 121, (2020) (PubMed).: "MYD88 L265P mutation promoted malignant B cell resistance against T cell-mediated cytotoxicity via upregulating the IL-10/STAT3 cascade." in: International immunopharmacology, Vol. 64, pp. 394-400, (2019) (PubMed).
: "Enhanced gut barrier integrity sensitizes colon cancer to immune therapy." in: Oncoimmunology, Vol. 7, Issue 11, pp. e1498438, (2018) (PubMed).
: "Synthetic Lethal Screen Demonstrates That a JAK2 Inhibitor Suppresses a BCL6-dependent IL10RA/JAK2/STAT3 Pathway in High Grade B-cell Lymphoma." in: The Journal of biological chemistry, Vol. 291, Issue 32, pp. 16686-98, (2016) (PubMed).
: "cmvIL-10 stimulates the invasive potential of MDA-MB-231 breast cancer cells." in: PLoS ONE, Vol. 9, Issue 2, pp. e88708, (2014) (PubMed).
: "Regulation of interleukin-10 receptor ubiquitination and stability by beta-TrCP-containing ubiquitin E3 ligase." in: PLoS ONE, Vol. 6, Issue 11, pp. e27464, (2011) (PubMed).
: "Role for IL-10 in suppression mediated by peptide-induced regulatory T cells in vivo." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 170, Issue 3, pp. 1240-8, (2003) (PubMed).
: "Regulatory activity of autocrine IL-10 on dendritic cell functions." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 166, Issue 7, pp. 4312-8, (2001) (PubMed).
: "Cutting edge: interactions through the IL-10 receptor regulate autoimmune diabetes." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 167, Issue 11, pp. 6087-91, (2001) (PubMed).
: "IL-10 inhibits macrophage activation and proliferation by distinct signaling mechanisms: evidence for Stat3-dependent and -independent pathways." in: The EMBO journal, Vol. 17, Issue 4, pp. 1006-18, (1998) (PubMed).
Aliases for IL-10RA 抗体
interleukin 10 receptor subunit alpha (IL10RA) 抗体interleukin 10 receptor, alpha (Il10ra) 抗体
interleukin 10 receptor subunit alpha (Il10ra) 抗体
AW553859 抗体
CD210 抗体
CD210a 抗体
CDw210 抗体
CDW210A 抗体
CDw210a 抗体
HIL-10R 抗体
IL-10R1 抗体
IL10R 抗体
Il10r 抗体
IL10R1 抗体
IL10RA 抗体
mIL-10R 抗体
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