IFIH1 抗体
(Interferon Induced with Helicase C Domain 1 (IFIH1))
DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein that is upregulated in response to treatment with beta-interferon and a protein kinase C-activating compound, mezerein. Irreversible reprogramming of melanomas can be achieved by treatment with both these agents\; treatment with either agent alone only achieves reversible differentiation. Genetic variation in this gene is associated with diabetes mellitus insulin-dependent type 19. [provided by RefSeq, Jul 2012].
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Latest Publications for our IFIH1 抗体
: "DDX39B interacts with the pattern recognition receptor pathway to inhibit NF-κB and sensitize to alkylating chemotherapy." in: BMC biology, Vol. 18, Issue 1, pp. 32, (2020) (PubMed).: "TREM-1 activation modulates dsRNA induced antiviral immunity with specific enhancement of MAPK signaling and the RLRs and TLRs on macrophages." in: Experimental cell research, Vol. 345, Issue 1, pp. 70-81, (2016) (PubMed).
: "Amplified RLR signaling activation through an interferon-stimulated gene-endoplasmic reticulum stress-mitochondrial calcium uniporter protein loop." in: Scientific reports, Vol. 6, pp. 20158, (2016) (PubMed).
: "TBK1-associated protein in endolysosomes (TAPE)/CC2D1A is a key regulator linking RIG-I-like receptors to antiviral immunity." in: The Journal of biological chemistry, Vol. 287, Issue 38, pp. 32216-21, (2012) (PubMed).
: "SerpinB9 expression in human renal tubular epithelial cells is induced by triggering of the viral dsRNA sensors TLR3, MDA5 and RIG-I." in: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, Vol. 27, Issue 7, pp. 2746-54, (2012) (PubMed).
: "A comprehensive analysis of pattern recognition receptors in normal and inflamed human epidermis: upregulation of dectin-1 in psoriasis." in: The Journal of investigative dermatology, Vol. 130, Issue 11, pp. 2611-20, (2010) (PubMed).
: "RNA helicase encoded by melanoma differentiation-associated gene 5 is a major autoantigen in patients with clinically amyopathic dermatomyositis: Association with rapidly progressive interstitial ..." in: Arthritis and rheumatism, Vol. 60, Issue 7, pp. 2193-200, (2009) (PubMed).
: "Role of retinoic acid inducible gene-I in human metapneumovirus-induced cellular signalling." in: The Journal of general virology, Vol. 89, Issue Pt 8, pp. 1978-86, (2008) (PubMed).
: "Identification of human metapneumovirus-induced gene networks in airway epithelial cells by microarray analysis." in: Virology, Vol. 374, Issue 1, pp. 114-27, (2008) (PubMed).
: "Manipulation of the nuclear factor-kappaB pathway and the innate immune response by viruses." in: Oncogene, Vol. 25, Issue 51, pp. 6844-67, (2006) (PubMed).
Aliases for IFIH1 抗体
interferon induced with helicase C domain 1 (IFIH1) 抗体interferon induced with helicase C domain 1 (Ifih1) 抗体
9130009C22Rik 抗体
Helicard 抗体
Hlcd 抗体
IDDM19 抗体
MDA-5 抗体
MDA5 抗体
RGD1560496 抗体
RLR-2 抗体
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