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IFIH1 抗体 (AA 976-1025)

The 兔 多克隆 anti-IFIH1 antibody is suitable to detect IFIH1 in samples from 人 和 小鼠. It has been validated for WB, IHC, ELISA 和 IF.
产品编号 ABIN1534105
发货至: 中国
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for IFIH1 抗体 (AA 976-1025) (ABIN1534105)

抗原

See all IFIH1 抗体
IFIH1 (Interferon Induced with Helicase C Domain 1 (IFIH1))

适用

  • 55
  • 13
  • 4
  • 2
  • 2
  • 2
  • 1
人, 小鼠

宿主

  • 46
  • 8
  • 2
  • 2
兔

克隆类型

  • 36
  • 22
多克隆

标记

  • 43
  • 4
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This IFIH1 antibody is un-conjugated

应用范围

  • 43
  • 19
  • 17
  • 17
  • 14
  • 6
  • 5
  • 2
  • 2
Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)
  • 抗原表位

    • 5
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 976-1025

    原理

    MDA5 Antibody

    特异性

    MDA5 Polyclonal Antibody detects endogenous levels of MDA5 protein.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

    纯度

    > 95 %

    免疫原

    The antiserum was produced against synthesized peptide derived from human IFIH1. AA range:976-1025

    亚型

    IgG
  • 应用备注

    WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:40000.. IF 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C/1 year

    有效期

    12 months
  • 抗原

    IFIH1 (Interferon Induced with Helicase C Domain 1 (IFIH1))

    别名

    IFIH1

    背景

    Synonyms: IFIH1, MDA5, RH116, Interferon-induced helicase C domain-containing protein 1, Clinically amyopathic dermatomyositis autoantigen 140 kDa, CADM-140 autoantigen, Helicase with 2 CARD domains, Helicard, Interferon-induced with helicase C domai

    Background: DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division.This gene encodes a DEAD box protein that is upregulated in response to treatment with beta-interferon and a protein kinase C-activating compound, mezerein. Irreversible reprogramming of melanomas can be achieved by treatment with both these agents, treatment with either agent alone only achieves reversible differentiation. Genetic variation in this gene is associated with diabetes mellitus insulin-depend

    Gene Name: IFIH1

    Protein Name: Interferon-induced helicase C domain-containing protein 1

    分子量

    116 kDa

    基因ID

    64135

    OMIM

    606951

    UniProt

    Q9BYX4

    途径

    Activation of Innate immune Response
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