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IFIH1 抗体 (AA 78-555)
IFIH1
适用: 人
WB, ELISA, IP
宿主: 小鼠
Monoclonal
Hely-1
unconjugated
IFIH1抗体详情
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抗原
See all IFIH1 抗体
IFIH1
(Interferon Induced with Helicase C Domain 1 (IFIH1))
抗原表位
All epitopes for IFIH1 抗体
AA 78-555
适用
All reactivities for IFIH1 抗体
人
宿主
All hosts for IFIH1 抗体
小鼠
克隆类型
All clonalities for IFIH1 抗体
单克隆
标记
All conjugates for IFIH1 抗体
This IFIH1 antibody is un-conjugated
应用范围
All applications for IFIH1 抗体
Western Blotting (WB), ELISA, Immunoprecipitation (IP)
特异性
Recognizes human MDA5.
交叉反应
人
纯化方法
Purified from concentrated hybridoma tissue culture supernatant.
纯度
>95 % (SDS-PAGE)
免疫原
Recombinant human MDA5 (aa 78-555).
克隆位点
Hely-1
亚型
IgG1
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Alternatives
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使用细节
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应用备注
Optimal working dilution should be determined by the investigator.
限制
仅限研究用
贮存及处理
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状态
Liquid
浓度
Lot specific
缓冲液
In PBS containing 10 % glycerol and 0.02 % sodium azide.
储存液
Sodium azide
注意事项
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
储存条件
4 °C,-20 °C
储存方法
Short Term Storage: +4°C Long Term Storage: -20°C Stable for at least 1 year after receipt when stored at -20°C.
有效期
12 months
IFIH1目标详情
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抗原
IFIH1
(Interferon Induced with Helicase C Domain 1 (IFIH1))
别名
MDA5 (IFIH1 产品 )
别名
MDA5 antibody, Hlcd antibody, IDDM19 antibody, MDA-5 antibody, RLR-2 antibody, 9130009C22Rik antibody, Helicard antibody, RGD1560496 antibody, interferon induced with helicase C domain 1 antibody, IFIH1 antibody, Ifih1 antibody
背景
RIG-I and MDA5 are highly conserved helicases involved in the innate immune response to virus. RIG-I is a member of the DEAD-box RNA helicases and is activated by cytoplasmic dsRNA and 5'-ppp RNA produced during the viral replication. The protein is characterized by a N-terminal region with two caspase recruitment domains (CARD) and a C-terminal region harboring potential ATP-dependent RNA helicase activity. RIG-1 recruits the CARD adaptor inducing IFN-beta (Cardif) in a CARD-CARD-dependent manner resulting in NF-kappaB and IRF3 activation.
UniProt
Q9BYX4
途径
Activation of Innate immune Response
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