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IFIH1 抗体 (AA 78-555)

IFIH1 适用: 人 WB, ELISA, IP 宿主: 小鼠 Monoclonal Hely-1 unconjugated
产品编号 ABIN1169453
发货至: 中国
  • 抗原 See all IFIH1 抗体
    IFIH1 (Interferon Induced with Helicase C Domain 1 (IFIH1))
    抗原表位
    • 5
    • 5
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 78-555
    适用
    • 41
    • 14
    • 4
    • 2
    • 2
    • 2
    • 1
    宿主
    • 34
    • 7
    • 2
    小鼠
    克隆类型
    • 35
    • 8
    单克隆
    标记
    • 32
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This IFIH1 antibody is un-conjugated
    应用范围
    • 28
    • 16
    • 14
    • 9
    • 7
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunoprecipitation (IP)
    特异性
    Recognizes human MDA5.
    交叉反应
    纯化方法
    Purified from concentrated hybridoma tissue culture supernatant.
    纯度
    >95 % (SDS-PAGE)
    免疫原
    Recombinant human MDA5 (aa 78-555).
    克隆位点
    Hely-1
    亚型
    IgG1
    Top Product
    Discover our top product IFIH1 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    In PBS containing 10 % glycerol and 0.02 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Short Term Storage: +4°C
    Long Term Storage: -20°C
    Stable for at least 1 year after receipt when stored at -20°C.
    有效期
    12 months
  • 抗原
    IFIH1 (Interferon Induced with Helicase C Domain 1 (IFIH1))
    别名
    MDA5 (IFIH1 产品)
    别名
    MDA5 antibody, Hlcd antibody, IDDM19 antibody, MDA-5 antibody, RLR-2 antibody, 9130009C22Rik antibody, Helicard antibody, RGD1560496 antibody, interferon induced with helicase C domain 1 antibody, IFIH1 antibody, Ifih1 antibody
    背景
    RIG-I and MDA5 are highly conserved helicases involved in the innate immune response to virus. RIG-I is a member of the DEAD-box RNA helicases and is activated by cytoplasmic dsRNA and 5'-ppp RNA produced during the viral replication. The protein is characterized by a N-terminal region with two caspase recruitment domains (CARD) and a C-terminal region harboring potential ATP-dependent RNA helicase activity. RIG-1 recruits the CARD adaptor inducing IFN-beta (Cardif) in a CARD-CARD-dependent manner resulting in NF-kappaB and IRF3 activation.
    UniProt
    Q9BYX4
    途径
    Activation of Innate immune Response
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