HJURP 抗体
(Holliday Junction Recognition Protein (HJURP))
Centromeric protein that plays a central role in the incorporation and maintenance of histone H3-like variant CENPA at centromeres. Acts as a specific chaperone for CENPA and is required for the incorporation of newly synthesized CENPA molecules into nucleosomes at replicated centromeres. Prevents CENPA-H4 tetramerization and prevents premature DNA binding by the CENPA-H4 tetramer. Directly binds Holliday junctions (By similarity).
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Latest Publications for our HJURP 抗体
: "Prognostic significance of EDN/RB, HJURP, p60/CAF-1 and PDLI4, four new markers in high-grade gliomas." in: PLoS ONE, Vol. 8, Issue 9, pp. e73332, (2013) (PubMed).: "HJURP binds CENP-A via a highly conserved N-terminal domain and mediates its deposition at centromeres." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 107, Issue 4, pp. 1349-54, (2010) (PubMed).
: "The expression level of HJURP has an independent prognostic impact and predicts the sensitivity to radiotherapy in breast cancer." in: Breast cancer research : BCR, Vol. 12, Issue 2, pp. R18, (2010) (PubMed).
Aliases for HJURP 抗体
Holliday junction recognition protein (Hjurp) 抗体Holliday junction recognition protein (HJURP) 抗体
C330011F01Rik 抗体
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