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HEYL 产品

(Hairy/enhancer-of-Split Related with YRPW Motif-Like (HEYL))

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This gene encodes a member of the hairy and enhancer of split-related (HESR) family of basic helix-loop-helix (bHLH)-type transcription factors. The sequence of the encoded protein contains a conserved bHLH and orange domain, but its YRPW motif has diverged from other HESR family members. It is thought to be an effector of Notch signaling and a regulator of cell fate decisions. Alternatively spliced transcript variants have been found, but their biological validity has not been determined. [provided by RefSeq, Jul 2008].

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Featured HEYL Categories

HEYL 抗体

High quality antibodies with extensive validation data.

HEYL 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended HEYL 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, ELISA, IF, IHC (p)
Validations
  • (1)
  • (6)
Cat. No. ABIN525732
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IF
Validations
  • (1)
  • (5)
Cat. No. ABIN525730
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (5)
Cat. No. ABIN525735
Quantity 100 μg
Datasheet Datasheet

Recommended HEYL 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
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Cat. No. ABIN1306577
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1306576
Quantity 25 μg
Datasheet Datasheet
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
Cat. No. ABIN3081312
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our HEYL Products

Gomi, Arbelaez, Crystal, Walters: "Activation of NOTCH1 or NOTCH3 signaling skews human airway basal cell differentiation toward a secretory pathway." in: PLoS ONE, Vol. 10, Issue 2, pp. e0116507, (2015) (PubMed).

Kuo, Jian, Li, Wan, Weng, Fang, Wu, Cheng: "Epigenetic inactivation of transforming growth factor-?1 target gene HEYL, a novel tumor suppressor, is involved in the P53-induced apoptotic pathway in hepatocellular carcinoma." in: Hepatology research : the official journal of the Japan Society of Hepatology, (2014) (PubMed).

Lavery, Villaronga, Walker, Patel, Belandia, Bevan: "Repression of androgen receptor activity by HEYL, a third member of the Hairy/Enhancer-of-split-related family of Notch effectors." in: The Journal of biological chemistry, Vol. 286, Issue 20, pp. 17796-808, (2011) (PubMed).

Morrow, Cullen, Liu, Guha, Sweeney, Birney, Collins, Walls, Redmond, Cahill: "Sonic Hedgehog induces Notch target gene expression in vascular smooth muscle cells via VEGF-A." in: Arteriosclerosis, thrombosis, and vascular biology, Vol. 29, Issue 7, pp. 1112-8, (2009) (PubMed).

Synonyms and alternative names related to HEYL

hes related family bHLH transcription factor with YRPW motif-like (HEYL), hairy/enhancer-of-split related with YRPW motif-like (Heyl), hes-related family bHLH transcription factor with YRPW motif-like (Heyl), hes-related family bHLH transcription factor with YRPW motif-like (heyl), bHLHb33, fk74e12, HESR3, hesr3, HEY3, Hey3, HRT3, Hrt3, wu:fk74e12

Protein level used designations for HEYL

  • HEY-like protein
  • HRT-3
  • class B basic helix-loop-helix protein 33
  • hHRT3
  • hHeyL
  • hairy-related transcription factor 3
  • hairy/enhancer-of-split related with YRPW motif 3
  • hairy/enhancer-of-split related with YRPW motif-like protein
  • hairy and enhance of split related 3
  • hairy and enhancer of split-related protein 3
  • mHRT3
  • basic helix-loop-helix transcription factor heyL
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