Hexosaminidase A 产品
(Hexosaminidase A (HEXA))
Categories
This gene encodes the alpha subunit of the lysosomal enzyme beta-hexosaminidase that, together with the cofactor GM2 activator protein, catalyzes the degradation of the ganglioside GM2, and other molecules containing terminal N-acetyl hexosamines. Beta-hexosaminidase is composed of two subunits, alpha and beta, which are encoded by separate genes. Both beta-hexosaminidase alpha and beta subunits are members of family 20 of glycosyl hydrolases. Mutations in the alpha or beta subunit genes lead to an accumulation of GM2 ganglioside in neurons and neurodegenerative disorders termed the GM2 gangliosidoses. Alpha subunit gene mutations lead to Tay-Sachs disease (GM2-gangliosidosis type I). [provided by RefSeq, Jul 2009].
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Featured Hexosaminidase A Categories
Hexosaminidase A 抗体
High quality antibodies with extensive validation data.
Hexosaminidase A ELISA试剂盒
Reliable ELISA kits for a wide range of species.
Hexosaminidase A 蛋白
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended Hexosaminidase A 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IHC, IP, ICC
Validations
- (5)
Cat. No.
ABIN7431284
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
IHC
Validations
- (5)
Cat. No.
ABIN7256120
Quantity
200 μL
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, ELISA, IHC (p)
Validations
- (5)
Cat. No.
ABIN3187766
Quantity
100 μL
Datasheet
Datasheet
Recommended Hexosaminidase A ELISA试剂盒
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6965158
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6962983
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6956519
Quantity
96 tests
Datasheet
Datasheet
Recommended Hexosaminidase A 蛋白
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1306559
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Insect Cells
Validations
- (1)
Cat. No.
ABIN3081378
Quantity
1 mg
Datasheet
Datasheet
Reactivity
Mouse
Source
Insect Cells
Validations
- (1)
Cat. No.
ABIN3133625
Quantity
1 mg
Datasheet
Datasheet
Latest Publications for our Hexosaminidase A Products
: "Reversal of Pathologic Lipid Accumulation in NPC1-Deficient Neurons by Drug-Promoted Release of LAMP1-Coated Lamellar Inclusions." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 36, Issue 30, pp. 8012-25, (2016) (PubMed).: "Improving accuracy of Tay Sachs carrier screening of the non-Jewish population: analysis of 34 carriers and six late-onset patients with HEXA enzyme and DNA sequence analysis." in: Pediatric research, Vol. 67, Issue 2, pp. 217-20, (2010) (PubMed).
: "Hexosaminidase as a new potential marker for larynx cancer." in: Clinical biochemistry, Vol. 42, Issue 10-11, pp. 1187-9, (2009) (PubMed).
Synonyms and alternative names related to Hexosaminidase A
hexosaminidase subunit alpha (HEXA), hexosaminidase B (beta polypeptide) (hexb), CUGBP Elav-like family member 6 (CELF6), hexosaminidase A (Hexa), hexosaminidase subunit alpha (Hexa), hexosaminidase A (alpha polypeptide) (hexa), beta-hexosaminidase subunit alpha-like (LOC100228061), fc04h11, Hex-1, HEXA, si:dkey-35i22.2, TSD, wu:fc04h11, wu:fv09f06, zgc:112084Protein level used designations for Hexosaminidase A
- N-acetyl-beta-glucosaminidase subunit alpha
- beta-N-acetylhexosaminidase subunit alpha
- beta-hexosaminidase subunit alpha
- hexosaminidase subunit A
- beta-hexosaminidase subunit beta
- beta-hexosaminidase alpha chain
- hexosaminidase A (alpha polypeptide)
- beta-hexosaminidase alpha-subunit
- hexosaminidase A alpha
- Hexose aminidase A (alpha polypeptide)
- hexosaminidase A
- Beta-hexosaminidase alpha chain
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