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HDAC4 抗体

(Histone Deacetylase 4 (HDAC4))
Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class II of the histone deacetylase/acuc/apha family. It possesses histone deacetylase activity and represses transcription when tethered to a promoter. This protein does not bind DNA directly, but through transcription factors MEF2C and MEF2D. It seems to interact in a multiprotein complex with RbAp48 and HDAC3. [provided by RefSeq, Jul 2008].

Active filters:

  • 抗原: HDAC4
  • Primary
Catalog no. 产品 适用 宿主 / 克隆类型 应用 价格和交货时间
ABIN5557843
HDAC4 抗体 (Biotin) HDAC4 · Primary Antibody 人, 小鼠, 大鼠, 猴 兔 Polyclonal
  • WB (Western Blotting: 所列应用)
  • ELISA (ELISA: 所列应用)
  • IHC (Immunohistochemistry: 所列应用)
  • IP (Immunoprecipitation: 所列应用)
  • 100 μg
发货至: 中国
ABIN5867645
HDAC4 抗体 (AA 456-592) HDAC4 · Primary Antibody 人 小鼠 Monoclonal
  • WB (Western Blotting: 所列应用)
  • ELISA (ELISA: 所列应用)
  • IHC (Immunohistochemistry: 所列应用)
  • FACS (Flow Cytometry: 所列应用)
  • IF/ICC (Immunofluorescence (fixed cells): 所列应用)
  • 100 μL
发货至: 中国
ABIN5867646
HDAC4 抗体 (N-Term) HDAC4 · Primary Antibody 人 小鼠 Monoclonal
  • WB (Western Blotting: 所列应用)
  • ELISA (ELISA: 所列应用)
  • IF/ICC (Immunofluorescence (fixed cells): 所列应用)
  • 100 μL
发货至: 中国
ABIN8121986
HDAC4 抗体 HDAC4 · Primary Antibody 人, 小鼠, 大鼠 兔 Monoclonal 克隆位点 AB2064
  • WB (Western Blotting: 所列应用)
  • ELISA (ELISA: 所列应用)
  • IHC (Immunohistochemistry: 所列应用)
  • IF (Immunofluorescence: 所列应用)
  • IP (Immunoprecipitation: 所列应用)
  • 20 μL
发货至: 中国
Primary Antibody
  • WB (Western Blotting: 所列应用)
  • ELISA (ELISA: 所列应用)
  • IHC (Immunohistochemistry: 所列应用)
  • IP (Immunoprecipitation: 所列应用)
适用
人, 小鼠, 大鼠, 猴
宿主
兔
克隆形成能力
Polyclonal
标记
Biotin
产品编号 ABIN5557843
Primary Antibody
  • WB (Western Blotting: 所列应用)
  • ELISA (ELISA: 所列应用)
  • IHC (Immunohistochemistry: 所列应用)
  • FACS (Flow Cytometry: 所列应用)
  • IF/ICC (Immunofluorescence (fixed cells): 所列应用)
适用
人
宿主
小鼠
克隆形成能力
Monoclonal
标记
unconjugated
抗体亚型
IgG1
抗原表位
AA 456-592
产品编号 ABIN5867645
Primary Antibody
  • WB (Western Blotting: 所列应用)
  • ELISA (ELISA: 所列应用)
  • IF/ICC (Immunofluorescence (fixed cells): 所列应用)
适用
人
宿主
小鼠
克隆形成能力
Monoclonal
标记
unconjugated
抗体亚型
IgG2a
抗原表位
N-Term
产品编号 ABIN5867646
Primary Antibody
  • WB (Western Blotting: 所列应用)
  • ELISA (ELISA: 所列应用)
  • IHC (Immunohistochemistry: 所列应用)
  • IF (Immunofluorescence: 所列应用)
  • IP (Immunoprecipitation: 所列应用)
适用
人, 小鼠, 大鼠
宿主
兔
克隆形成能力
Monoclonal
克隆
AB2064
标记
unconjugated
抗体亚型
IgG
产品编号 ABIN8121986

Latest Publications for our HDAC4 抗体

Karppinen, Hänninen, Rapila, Tavi: "Sarcoplasmic reticulum Ca2+ -induced Ca2+ release regulates class IIa HDAC localization in mouse embryonic cardiomyocytes." in: Physiological reports, Vol. 6, Issue 2, (2019) (PubMed).

Sirchia, Faversani, Rovina, Russo, Paganini, Savi, Augello, Rosso, Del Gobbo, Tabano, Bosari, Miozzo: "Epigenetic effects of chromatin remodeling agents on organotypic cultures." in: Epigenomics, Vol. 8, Issue 3, pp. 341-58, (2016) (PubMed).

Liu, Gu, Feng, Yang, Zhu, Lu, Qi: "Both HDAC5 and HDAC6 are required for the proliferation and metastasis of melanoma cells." in: Journal of translational medicine, Vol. 14, pp. 7, (2016) (PubMed).

Cao, Li, Zhu, Shen, Han, Zhang, Yu, Wang, Wu, Chen, Sun, Tang, Zhao, Qiao, Hou, Mao: "The antiparasitic clioquinol induces apoptosis in leukemia and myeloma cells by inhibiting histone deacetylase activity." in: The Journal of biological chemistry, Vol. 288, Issue 47, pp. 34181-9, (2013) (PubMed).

Isaacs, Antony, Dalrymple, Brennen, Gerber, Hammers, Wissing, Kachhap, Luo, Xing, Björk, Olsson, Björk, Leanderson: "Tasquinimod Is an Allosteric Modulator of HDAC4 survival signaling within the compromised cancer microenvironment." in: Cancer research, Vol. 73, Issue 4, pp. 1386-99, (2013) (PubMed).

Kornfeld, Biggar, Storey: "Differential expression of mature microRNAs involved in muscle maintenance of hibernating little brown bats, Myotis lucifugus: a model of muscle atrophy resistance." in: Genomics, proteomics & bioinformatics, Vol. 10, Issue 5, pp. 295-301, (2012) (PubMed).

Shao, Li, Zhang, Liu, Liu, Zhao, Shen, Li: "Involvement of histone deacetylation in MORC2-mediated down-regulation of carbonic anhydrase IX." in: Nucleic acids research, Vol. 38, Issue 9, pp. 2813-24, (2010) (PubMed).

Ficner: "Novel structural insights into class I and II histone deacetylases." in: Current topics in medicinal chemistry, Vol. 9, Issue 3, pp. 235-40, (2009) (PubMed).

Keedy, Archin, Gates, Espeseth, Hazuda, Margolis: "A limited group of class I histone deacetylases acts to repress human immunodeficiency virus type 1 expression." in: Journal of virology, Vol. 83, Issue 10, pp. 4749-56, (2009) (PubMed).

Chen, Cepko: "HDAC4 regulates neuronal survival in normal and diseased retinas." in: Science (New York, N.Y.), Vol. 323, Issue 5911, pp. 256-9, (2009) (PubMed).

Aliases for HDAC4 抗体

histone deacetylase 4 (PTRG_03699) 抗体
hypothetical protein (PGTG_15512) 抗体
Histone deacetylase 4 (HDAC4) 抗体
GF18710 gene product from transcript GF18710-RC (Dana\GF18710) 抗体
histone deacetylase 4 (HDAC4) 抗体
histone deacetylase 4 (Hdac4) 抗体
histone deacetylase 4 (hdac4) 抗体
4932408F19Rik 抗体
AHO3 抗体
AI047285 抗体
BDMR 抗体
CG1770 抗体
DanaGF18710 抗体
dana_GLEANR_19966 抗体
DHDAC4 抗体
dHDAC4 抗体
Dmel\\CG1770 抗体
dmHDA405 抗体
GC1770 抗体
GF18710 抗体
HA6116 抗体
HD4 抗体
HDAC 抗体
HDAC-4 抗体
HDAC-A 抗体
hdac4 抗体
HDAC4 抗体
HDAC4a 抗体
HDACA 抗体
wu:fa96d08 抗体
wu:fc56f08 抗体
zgc:152701 抗体
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