GSAP 抗体
(Pigeon Homolog (PION))
Accumulation of neurotoxic amyloid-beta is a major hallmark of Alzheimer disease (AD\; MIM 104300). Formation of amyloid-beta is catalyzed by gamma-secretase (see PSEN1\; MIM 104311), a protease with numerous substrates. PION, or GSAP, selectively increases amyloid-beta production through a mechanism involving its interaction with both gamma-secretase and its substrate, the amyloid-beta precursor protein (APP\; MIM 104760) C-terminal fragment (APP-CTF) (He et al., 2010 [PubMed 20811458]).[supplied by OMIM, Nov 2010].
Recommended next Filters:
12 results
Aliases for GSAP 抗体
gamma-secretase activating protein (GSAP) 抗体gamma-secretase activating protein (Gsap) 抗体
A530088I07Rik 抗体
PION 抗体
Pion 抗体
您还需要查找其他产品吗？
- GS28 抗体
- GRXCR1 抗体
- GRWD1 抗体
- GRSF1 抗体
- GRPR 抗体
- GRPEL2 抗体
- GRPEL1 抗体
- GRP94 抗体
- GRP78 抗体
- GRP 抗体
- Growth Hormone Regulated TBC Protein 1 抗体
- Growth Hormone Receptor 抗体
- Growth Hormone 2 抗体
- Growth Hormone 1 抗体
- Growth Arrest-Specific 1 抗体
- Growth Arrest and DNA-Damage-Inducible, beta 抗体
- GRO gamma 抗体
- GRM8 抗体
- GRM7 抗体
- GRM2 抗体
You are here:
