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- 抗原 See all GSAP (PION) 抗体
- GSAP (PION) (Pigeon Homolog (PION))
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抗原表位
- N-Term
- 适用
- 人, 大鼠, 马, 兔, Cow, 犬
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This GSAP antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- QTRQNELLYT FEKDLQVFSC SVNSERTLLA ASLVQSTKEG KRNELQPGSK
- 预测反应
- Cow: 85%, Dog: 85%, Horse: 93%, Human: 100%, Rabbit: 93%, Rat: 86%
- 产品特性
- This is a rabbit polyclonal antibody against GSAP. It was validated on Western Blot.
- 纯化方法
- Affinity purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the N-terminal region of Human GSAP
- Top Product
- Discover our top product PION Primary Antibody
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anti-Pigeon Homolog (PION) (AA 616-854) antibody
PION 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Pigeon Homolog (PION) (AA 536-565), (C-Term) antibodyPION 适用: 人 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
anti-Pigeon Homolog (PION) (C-Term) antibodyPION 适用: 人, 大鼠, 小鼠 WB, EIA 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- 抗原
- GSAP (PION) (Pigeon Homolog (PION))
- 别名
- GSAP (PION 产品)
- 别名
- PION antibody, A530088I07Rik antibody, Pion antibody, gamma-secretase activating protein antibody, GSAP antibody, Gsap antibody
- 背景
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Accumulation of neurotoxic amyloid-beta is a major hallmark of Alzheimer disease. Formation of amyloid-beta is catalyzed by gamma-secretase, a protease with numerous substrates. PION, or GSAP, selectively increases amyloid-beta production through a mechanism involving its interaction with both gamma-secretase and its substrate, the amyloid-beta precursor protein C-terminal fragment (APP-CTF).
Alias Symbols: GSAP, PION,
Protein Size: 854 - 基因ID
- 54103
- NCBI登录号
- NP_059135
- UniProt
- A4D1B5
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