This gene encodes a member of the GRB2/Sem5/Drk family. This member is an adaptor-like protein involved in leukocyte-specific protein-tyrosine kinase signaling. Like its related family member, GRB2-related adaptor protein (GRAP), this protein contains an SH2 domain flanked by two SH3 domains. This protein interacts with other proteins, such as GRB2-associated binding protein 1 (GAB1) and the SLP-76 leukocyte protein (LCP2), through its SH3 domains. Transcript variants utilizing alternative polyA sites exist. [provided by RefSeq, Jul 2008].
Latest Publications for our GRB2-Related Adaptor Protein 2 抗体
Yankee, Yun, Draves, Ganesh, Bevan, Murali-Krishna, Clark: "The Gads (GrpL) adaptor protein regulates T cell homeostasis." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 173, Issue 3, pp. 1711-20, (2004) (PubMed).
Yankee, Draves, Ewings, Clark, Graves: "CD95/Fas induces cleavage of the GrpL/Gads adaptor and desensitization of antigen receptor signaling." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 98, Issue 12, pp. 6789-93, (2001) (PubMed).
Qiu, Hua, Agrawal, Li, Cai, Chan, Zhou, Luo, Liu: "Molecular cloning and expression of human grap-2, a novel leukocyte-specific SH2- and SH3-containing adaptor-like protein that binds to gab-1." in: Biochemical and biophysical research communications, Vol. 253, Issue 2, pp. 443-7, (1999) (PubMed).
Aliases for GRB2-Related Adaptor Protein 2 抗体
GRB2-related adaptor protein 2 (GRAP2) 抗体 GRB2-related adaptor protein 2 (Grap2) 抗体 GRB2-related adaptor protein 2a (grap2a) 抗体 GRB2-related adaptor protein 2 (grap2) 抗体 GRB2-related adaptor protein 2b (grap2b) 抗体 GADS 抗体 Gads 抗体 GRAP-2 抗体 GRAP2 抗体 grap2 抗体 GRB2L 抗体 GRBLG 抗体 GrbX 抗体 Grf40 抗体 GRID 抗体 GRPL 抗体 GrpL 抗体 Mona 抗体 P38 抗体 zgc:65942 抗体 zgc:112091 抗体