GRAF 抗体
(rho GTPase Activating Protein 26 (ARHGAP26))
Interaction of a cell with the extracellular matrix triggers integrin cell surface receptors to begin signaling cascades that regulate the organization of the actin-cytoskeleton. One of the proteins involved in these cascades is focal adhesion kinase. The protein encoded by this gene is a GTPase activating protein that binds to focal adhesion kinase and mediates the activity of the GTP binding proteins RhoA and Cdc42. Defects in this gene are a cause of juvenile myelomonocytic leukemia (JMML). Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2010].
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Latest Publications for our GRAF 抗体
: "Novel signatures of cancer-associated fibroblasts." in: International journal of cancer, Vol. 133, Issue 2, pp. 286-93, (2013) (PubMed).: "Expression of cyclins-B and cyclins-e in individual molt-4 cells and in stimulated human-lymphocytes during their progression through the cell-cycle." in: International journal of oncology, Vol. 3, Issue 6, pp. 1037-42, (2011) (PubMed).
: "Rho proteins, mental retardation and the cellular basis of cognition." in: Trends in neurosciences, Vol. 25, Issue 4, pp. 191-9, (2002) (PubMed).
: "The human GRAF gene is fused to MLL in a unique t(5;11)(q31;q23) and both alleles are disrupted in three cases of myelodysplastic syndrome/acute myeloid leukemia with a deletion 5q." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 97, Issue 16, pp. 9168-73, (2000) (PubMed).
: "Independent binding of the retinoblastoma protein and p107 to the transcription factor E2F." in: Nature, Vol. 355, Issue 6356, pp. 176-9, (1992) (PubMed).
Aliases for GRAF 抗体
Rho GTPase activating protein 26 (ARHGAP26) 抗体Rho GTPase activating protein 26 (Arhgap26) 抗体
1810044B20Rik 抗体
2610010G17Rik 抗体
4933432P15Rik 抗体
AI853435 抗体
ARHGAP26 抗体
GRAF 抗体
GRAF1 抗体
mKIAA0621 抗体
OPHN1L 抗体
OPHN1L1 抗体
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