GPR68 抗体
(G Protein-Coupled Receptor 68 (GPR68))
Proton-sensing receptor involved in pH homeostasis. May represents an osteoblastic pH sensor regulating cell-mediated responses to acidosis in bone. Mediates its action by association with G proteins that stimulates inositol phosphate (IP) production or Ca(2+) mobilization. The receptor is almost silent at pH 7.8 but fully activated at pH 6.8 (By similarity). Function also as a metastasis suppressor gene in prostate cancer (By similarity).
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41 results
GPR68
适用: 人, 小鼠, 大鼠, 马, 兔, 犬, Pig
WB
宿主: 兔
Polyclonal
unconjugated
1 image
GPR68
适用: 人, 大鼠, 猴, Gibbon, Gorilla
ELISA, IHC
宿主: 兔
Polyclonal
unconjugated
1 image
GPR68
适用: 人, 马, Bat, Gibbon, Gorilla
ELISA, IHC
宿主: 兔
Polyclonal
unconjugated
1 image
GPR68
适用: 人
ELISA, IHC (p)
宿主: 兔
Polyclonal
unconjugated
1 image
Latest Publications for our GPR68 抗体
: "Metabolic acidosis increases intracellular calcium in bone cells through activation of the proton receptor OGR1." in: Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, Vol. 24, Issue 2, pp. 305-13, (2009) (PubMed).: "Ovarian cancer G protein-coupled receptor 1, a new metastasis suppressor gene in prostate cancer." in: Journal of the National Cancer Institute, Vol. 99, Issue 17, pp. 1313-27, (2007) (PubMed).
: "Convergent signaling by acidosis and receptor activator of NF-kappaB ligand (RANKL) on the calcium/calcineurin/NFAT pathway in osteoclasts." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 102, Issue 7, pp. 2643-8, (2005) (PubMed).
: "Sphingosylphosphorylcholine antagonizes proton-sensing ovarian cancer G-protein-coupled receptor 1 (OGR1)-mediated inositol phosphate production and cAMP accumulation." in: Journal of pharmacological sciences, Vol. 99, Issue 2, pp. 160-7, (2005) (PubMed).
Aliases for GPR68 抗体
G protein-coupled receptor 68 (GPR68) 抗体G protein-coupled receptor 68 (LOC100348269) 抗体
G protein-coupled receptor 68 (Gpr68) 抗体
BB131428 抗体
GPR12A 抗体
GPR68 抗体
OGR1 抗体
Ogr1 抗体
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