电话:
+86 (0512) 65829739
传真:
+86 (010) 6788 5057
电子邮件:
orders@antibodies-online.cn

GPR68 抗体

(G Protein-Coupled Receptor 68 (GPR68))
Proton-sensing receptor involved in pH homeostasis. May represents an osteoblastic pH sensor regulating cell-mediated responses to acidosis in bone. Mediates its action by association with G proteins that stimulates inositol phosphate (IP) production or Ca(2+) mobilization. The receptor is almost silent at pH 7.8 but fully activated at pH 6.8 (By similarity). Function also as a metastasis suppressor gene in prostate cancer (By similarity).

Active filters:

  • 抗原: GPR68
  • Primary
Catalog no. 产品 适用 宿主 / 克隆类型 应用 价格和交货时间
ABIN1735153
GPR68 抗体 (2nd Extracellular Domain) GPR68 · Primary Antibody 人 兔 Polyclonal
  • IHC (p) (Immunohistochemistry (Paraffin-embedded Sections): 所列应用)
  • 50 μg
发货至: 中国
ABIN1735155
GPR68 抗体 (C-Term) GPR68 · Primary Antibody 人, 大鼠 兔 Polyclonal
  • IHC (p) (Immunohistochemistry (Paraffin-embedded Sections): 所列应用)
  • 50 μg
发货至: 中国
Primary Antibody
  • IHC (p) (Immunohistochemistry (Paraffin-embedded Sections): 所列应用)
适用
人
宿主
兔
克隆形成能力
Polyclonal
标记
unconjugated
抗体亚型
IgG
抗原表位
2nd Extracellular Domain
产品编号 ABIN1735153
Primary Antibody
  • IHC (p) (Immunohistochemistry (Paraffin-embedded Sections): 所列应用)
适用
人, 大鼠
宿主
兔
克隆形成能力
Polyclonal
标记
unconjugated
抗体亚型
IgG
抗原表位
C-Term
产品编号 ABIN1735155

Latest Publications for our GPR68 抗体

Frick, Krieger, Nehrke, Bushinsky: "Metabolic acidosis increases intracellular calcium in bone cells through activation of the proton receptor OGR1." in: Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, Vol. 24, Issue 2, pp. 305-13, (2009) (PubMed).

Singh, Berk, Oates, Zhao, Tan, Jiang, Zhou, Kirmani, Steinmetz, Lindner, Xu: "Ovarian cancer G protein-coupled receptor 1, a new metastasis suppressor gene in prostate cancer." in: Journal of the National Cancer Institute, Vol. 99, Issue 17, pp. 1313-27, (2007) (PubMed).

Komarova, Pereverzev, Shum, Sims, Dixon: "Convergent signaling by acidosis and receptor activator of NF-kappaB ligand (RANKL) on the calcium/calcineurin/NFAT pathway in osteoclasts." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 102, Issue 7, pp. 2643-8, (2005) (PubMed).

Mogi, Tomura, Tobo, Wang, Damirin, Kon, Komachi, Hashimoto, Sato, Okajima: "Sphingosylphosphorylcholine antagonizes proton-sensing ovarian cancer G-protein-coupled receptor 1 (OGR1)-mediated inositol phosphate production and cAMP accumulation." in: Journal of pharmacological sciences, Vol. 99, Issue 2, pp. 160-7, (2005) (PubMed).

Aliases for GPR68 抗体

G protein-coupled receptor 68 (GPR68) 抗体
G protein-coupled receptor 68 (LOC100348269) 抗体
G protein-coupled receptor 68 (Gpr68) 抗体
BB131428 抗体
GPR12A 抗体
GPR68 抗体
OGR1 抗体
Ogr1 抗体
You are here: