GEN1 抗体
(Gen Endonuclease Homolog 1 (GEN1))
Endonuclease which resolves Holliday junctions by the introduction of symmetrically related cuts across the junction point, to produce nicked duplex products in which the nicks can be readily ligated. Four-way DNA intermediates, also known as Holliday junctions, are formed during homologous recombination and DNA repair, and their resolution is necessary for proper chromosome segregation.
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Latest Publications for our GEN1 抗体
: "SLX4 Prevents GEN1-Dependent DSBs During DNA Replication Arrest Under Pathological Conditions in Human Cells." in: Scientific reports, Vol. 7, pp. 44464, (2018) (PubMed).Aliases for GEN1 抗体
GEN1, Holliday junction 5' flap endonuclease (GEN1) 抗体GEN1, Holliday junction 5' flap endonuclease (Gen1) 抗体
GEN1 Holliday junction 5' flap endonuclease (Gen1) 抗体
5830483C08Rik 抗体
Gen 抗体
RGD1559792 抗体
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