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- 抗原 See all GEN1 抗体
- GEN1 (Gen Endonuclease Homolog 1 (GEN1))
- 适用
- 人, 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This GEN1 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 纯化方法
- Affinity purification
- 免疫原
- Recombinant protein of human GEN1
- 亚型
- IgG
- Top Product
- Discover our top product GEN1 Primary Antibody
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anti-Gen Endonuclease Homolog 1 (GEN1) (AA 669-908) antibody
GEN1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Gen Endonuclease Homolog 1 (GEN1) (AA 60-89), (N-Term) antibodyGEN1 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal RB23975 unconjugated
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- 应用备注
- WB 1:500 - 1:2000
- 限制
- 仅限研究用
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- 浓度
- 1 mg/mL
- 缓冲液
- Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- 抗原
- GEN1 (Gen Endonuclease Homolog 1 (GEN1))
- 别名
- GEN1 (GEN1 产品)
- 别名
- 5830483C08Rik antibody, Gen antibody, RGD1559792 antibody, GEN1, Holliday junction 5' flap endonuclease antibody, GEN1 Holliday junction 5' flap endonuclease antibody, GEN1 antibody, Gen1 antibody
- 背景
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Synonyms: DKFZp781F0986,Flap endonuclease GEN homolog 1,FLJ40869,GEN 1,Gen,Gen homolog 1 endonuclease (Drosophila),Gen homolog 1 endonuclease,GEN,GEN1
Background: This gene encodes a member of the Rad2/xeroderma pigmentosum group G nuclease family, whose members are characterized by N-terminal and internal xeroderma pigmentosum group G nuclease domains followed by helix-hairpin-helix domains and disordered C-terminal domains. The protein encoded by this gene is involved in resolution of Holliday junctions, which are intermediate four-way structures that covalently link DNA during homologous recombination and double-strand break repair. The protein resolves Holliday junctions by creating dual incisions across the junction to produce nicked duplex products that can be ligated. In addition, this protein has been found to localize to centrosomes where it has been implicated in regulation of centrosome integrity. Alternative splicing results in multiple transcript variants.
- 分子量
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Observed_MW: 103kDa
Calculated_MW: 102kDa
- 基因ID
- 348654
- UniProt
- Q17RS7
- 途径
- DNA Damage Repair
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