GDF5 蛋白
(Growth Differentiation Factor 5 (GDF5))
The protein encoded by this gene is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. This group of proteins is characterized by a polybasic proteolytic processing site which is cleaved to produce a mature protein containing seven conserved cysteine residues. The members of this family are regulators of cell growth and differentiation in both embryonic and adult tissues. Mutations in this gene are associated with acromesomelic dysplasia, Hunter-Thompson type\; brachydactyly, type C\; and chondrodysplasia, Grebe type. These associations confirm that the gene product plays a role in skeletal development. [provided by RefSeq, Jul 2008].
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Latest Publications for our GDF5 蛋白
: "Identification of small molecular compounds and fabrication of its aqueous solution by laser-ablation, expanding primordial cartilage." in: Osteoarthritis and cartilage, Vol. 19, Issue 2, pp. 233-41, (2011) (PubMed).
: "Combined use of bFGF and GDF-5 enhances the healing of medial collateral ligament injury." in: Biochemical and biophysical research communications, Vol. 402, Issue 2, pp. 329-34, (2010) (PubMed).
: "Combined use of bFGF and GDF-5 enhances the healing of medial collateral ligament injury." in: Biochemical and biophysical research communications, Vol. 402, Issue 2, pp. 329-34, (2010) (PubMed).
Aliases for GDF5 蛋白
growth differentiation factor 5 L homeolog (gdf5.L) 蛋白growth differentiation factor 5 (GDF5) 蛋白
growth differentiation factor 5 (Gdf5) 蛋白
BDA1C 蛋白
BMP14 蛋白
bp 蛋白
brp 蛋白
Cdmp-1 蛋白
CDMP1 蛋白
Cdmp1 蛋白
gdf 蛋白
gdf-5 蛋白
GDF5 蛋白
LAP4 蛋白
OS5 蛋白
SYM1B 蛋白
SYNS2 蛋白
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