GCLM 抗体
(Glutamate-Cysteine Ligase, Modifier Subunit (GCLM))
Glutamate-cysteine ligase, also known as gamma-glutamylcysteine synthetase, is the first rate limiting enzyme of glutathione synthesis. The enzyme consists of two subunits, a heavy catalytic subunit and a light regulatory subunit. Gamma glutamylcysteine synthetase deficiency has been implicated in some forms of hemolytic anemia. [provided by RefSeq, Jul 2008].
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70 results
GCLM
适用: 人
WB, IP, IHC (p)
宿主: 兔
Monoclonal
R05-2C5
unconjugated
Recombinant Antibody
Latest Publications for our GCLM 抗体
: "A Genome-wide Haploid Genetic Screen Identifies Regulators of Glutathione Abundance and Ferroptosis Sensitivity." in: Cell reports, Vol. 26, Issue 6, pp. 1544-1556.e8, (2019) (PubMed).: "Oregano Essential Oil Induces SOD1 and GSH Expression through Nrf2 Activation and Alleviates Hydrogen Peroxide-Induced Oxidative Damage in IPEC-J2 Cells." in: Oxidative medicine and cellular longevity, Vol. 2016, pp. 5987183, (2017) (PubMed).
: "Silymarin protects against acrylamide-induced neurotoxicity via Nrf2 signalling in PC12 cells." in: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, Vol. 102, pp. 93-101, (2017) (PubMed).
: "Chemotherapy triggers HIF-1-dependent glutathione synthesis and copper chelation that induces the breast cancer stem cell phenotype." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 112, Issue 33, pp. E4600-9, (2015) (PubMed).
: "Molecular mechanisms of lipopolysaccharide-mediated inhibition of glutathione synthesis in mice." in: Free radical biology & medicine, Vol. 68, pp. 148-58, (2014) (PubMed).
: "The protective role of resveratrol in the sodium arsenite-induced oxidative damage via modulation of intracellular GSH homeostasis." in: Biological trace element research, Vol. 155, Issue 1, pp. 119-31, (2014) (PubMed).
: "Mechanism and significance of changes in glutamate-cysteine ligase expression during hepatic fibrogenesis." in: The Journal of biological chemistry, Vol. 287, Issue 43, pp. 36341-55, (2012) (PubMed).
: "Molecular and functional characterizations of gastrula organizer cells derived from human embryonic stem cells." in: Stem cells (Dayton, Ohio), Vol. 29, Issue 4, pp. 600-8, (2011) (PubMed).
: "Protection against 2-chloroethyl ethyl sulfide (CEES)-induced cytotoxicity in human keratinocytes by an inducer of the glutathione detoxification pathway." in: Toxicology and applied pharmacology, Vol. 255, Issue 2, pp. 176-83, (2011) (PubMed).
: "Diversity in antioxidant response enzymes in progressive stages of human nonalcoholic fatty liver disease." in: Drug metabolism and disposition: the biological fate of chemicals, Vol. 38, Issue 12, pp. 2293-301, (2010) (PubMed).
Aliases for GCLM 抗体
glutamate-cysteine ligase regulatory subunit (PTRG_09814) 抗体glutamate cysteine ligase, modifier subunit (Gclm) 抗体
glutamate-cysteine ligase modifier subunit (GCLM) 抗体
glutamate-cysteine ligase, modifier subunit (gclm) 抗体
glutamate-cysteine ligase, modifier subunit L homeolog (gclm.L) 抗体
glutamate-cysteine ligase, modifier subunit (Gclm) 抗体
glutamate-cysteine ligase modifier subunit (Gclm) 抗体
AI649393 抗体
Gcmc 抗体
Glclr 抗体
GLCLR 抗体
id:ibd3182 抗体
wu:fi24c07 抗体
zgc:55903 抗体
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