(Guanylate Binding Protein 2, Interferon-Inducible (GBP2))
Interferons are cytokines that have antiviral effects and inhibit tumor cell proliferation. They induce a large number of genes in their target cells, including those coding for the guanylate-binding proteins (GBPs). GBPs are characterized by their ability to specifically bind guanine nucleotides (GMP, GDP, and GTP). The protein encoded by this gene is a GTPase that converts GTP to GDP and GMP. [provided by RefSeq, Jul 2008].
Mori, Sasaki, Makabe, Yoshinari, Yajima: "The genes Scgb1a1, Lpo and Gbp2 characteristically expressed in peri-implant epithelium of rats." in: Clinical oral implants research, (2015) (PubMed).
Hall, Baer, Shah, Criswell, Shiboski, Rosen, Casciola-Rosen: "Molecular Subsetting of Interferon Pathways in Sjögren's Syndrome." in: Arthritis & rheumatology (Hoboken, N.J.), Vol. 67, Issue 9, pp. 2437-46, (2015) (PubMed).
Hall, Casciola-Rosen, Berger, Kapsogeorgou, Cheadle, Tzioufas, Baer, Rosen: "Precise probes of type II interferon activity define the origin of interferon signatures in target tissues in rheumatic diseases." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 109, Issue 43, pp. 17609-14, (2012) (PubMed).
Cheng, Patterson, Staeheli: "Interferon-induced guanylate-binding proteins lack an N(T)KXD consensus motif and bind GMP in addition to GDP and GTP." in: Molecular and cellular biology, Vol. 11, Issue 9, pp. 4717-25, (1991) (PubMed).
Aliases for GBP2 抗体
guanylate binding protein 2 (GBP2) 抗体 guanylate binding protein 2 (Gbp2) 抗体 guanylate binding protein 2, interferon-inducible (GBP2) 抗体 GTP binding protein 2 L homeolog (gtpbp2.L) 抗体