FHIT 抗体
(Fragile Histidine Triad (FHIT))
This gene, a member of the histidine triad gene family, encodes a diadenosine 5',5'''-P1,P3-triphosphate hydrolase involved in purine metabolism. The gene encompasses the common fragile site FRA3B on chromosome 3, where carcinogen-induced damage can lead to translocations and aberrant transcripts of this gene. In fact, aberrant transcripts from this gene have been found in about half of all esophageal, stomach, and colon carcinomas. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Oct 2009].
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Latest Publications for our FHIT 抗体
: "FHIT, a Novel Modifier Gene in Pulmonary Arterial Hypertension." in: American journal of respiratory and critical care medicine, Vol. 199, Issue 1, pp. 83-98, (2019) (PubMed).: "High-resolution whole-genome analysis of skull base chordomas implicates FHIT loss in chordoma pathogenesis." in: Neoplasia (New York, N.Y.), Vol. 14, Issue 9, pp. 788-98, (2012) (PubMed).
: "CpG island hypermethylation of multiple tumor suppressor genes associated with loss of their protein expression during rat lung carcinogenesis induced by 3-methylcholanthrene and diethylnitrosamine." in: Biochemical and biophysical research communications, Vol. 402, Issue 3, pp. 507-14, (2010) (PubMed).
: "Neuroprotective properties of picroside II in a rat model of focal cerebral ischemia." in: International journal of molecular sciences, Vol. 11, Issue 11, pp. 4580-90, (2010) (PubMed).
: "The protein expression of TRP-1 and galectin-1 in cutaneous malignant melanomas." in: Cancer genomics & proteomics, Vol. 5, Issue 6, pp. 293-300, (2009) (PubMed).
: "Muir-Torre-like syndrome in Fhit-deficient mice." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 97, Issue 9, pp. 4742-7, (2000) (PubMed).
: "The Fhit tumor suppressor protein regulates the intracellular concentration of diadenosine triphosphate but not diadenosine tetraphosphate." in: Cancer research, Vol. 60, Issue 9, pp. 2342-4, (2000) (PubMed).
: "The FHIT gene, spanning the chromosome 3p14.2 fragile site and renal carcinoma-associated t(3;8) breakpoint, is abnormal in digestive tract cancers." in: Cell, Vol. 84, Issue 4, pp. 587-97, (1996) (PubMed).
: "Coxsackievirus B3: primary structure of the 5' non-coding and capsid protein-coding regions of the genome." in: Virus research, Vol. 3, Issue 3, pp. 263-70, (1986) (PubMed).
Aliases for FHIT 抗体
fragile histidine triad (FHIT) 抗体fragile histidine triad (Fhit) 抗体
fragile histidine triad gene (fhit) 抗体
fragile histidine triad gene (Fhit) 抗体
fragile histidine triad (fhit) 抗体
fragile histidine triad protein (PY07476) 抗体
fragile histidine triad L homeolog (fhit.L) 抗体
AP3Aase 抗体
AW045638 抗体
FHIT 抗体
FRA3B 抗体
Fra14A2 抗体
LOC100223655 抗体
zgc:73176 抗体
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