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FHIT 抗体 (pTyr114)

The 兔 多克隆 anti-FHIT antibody is suitable to detect FHIT in samples from 人, 小鼠 和 大鼠. It has been validated for ELISA, IHC 和 IF.
产品编号 ABIN1532181
发货至: 中国
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北京 101111
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Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for FHIT 抗体 (pTyr114) (ABIN1532181)

抗原

See all FHIT 抗体
FHIT (Fragile Histidine Triad (FHIT))

适用

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人, 小鼠, 大鼠

宿主

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兔

克隆类型

  • 90
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多克隆

标记

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This FHIT antibody is un-conjugated

应用范围

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ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
  • 抗原表位

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    AA 80-129, pTyr114

    原理

    Fhit (phospho Tyr114) Antibody

    特异性

    Phospho-Fhit (Y114) Polyclonal Antibody detects endogenous levels of Fhit protein only when phosphorylated at Y114.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

    纯度

    > 95 %

    免疫原

    The antiserum was produced against synthesized peptide derived from human FHIT around the phosphorylation site of Tyr114. AA range:80-129

    亚型

    IgG
  • 应用备注

    IHC 1:100 - 1:300. ELISA: 1:40000.. IF 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C/1 year

    有效期

    12 months
  • 抗原

    FHIT (Fragile Histidine Triad (FHIT))

    别名

    FHIT

    背景

    Synonyms: FHIT; Bis(5'-adenosyl)-triphosphatase; AP3A hydrolase; AP3Aase; Diadenosine 5'; 5'''-P1,P3-triphosphate hydrolase; Dinucleosidetriphosphatase; Fragile histidine triad protein

    Background: This gene, a member of the histidine triad gene family, encodes a diadenosine 5',5'''-P1,P3-triphosphate hydrolase involved in purine metabolism. The gene encompasses the common fragile site FRA3B on chromosome 3, where carcinogen-induced damage can lead to translocations and aberrant transcripts of this gene. In fact, aberrant transcripts from this gene have been found in about half of all esophageal, stomach, and colon carcinomas. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Oct 2009],

    Gene Name: FHIT

    Protein Name: Bis(5'-adenosyl)-triphosphatase

    分子量

    16 kDa

    基因ID

    2272

    OMIM

    144700

    UniProt

    P49789
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