FCHO2 抗体
(FCH Domain Only 2 (FCHO2))
Functions in an early step of clathrin-mediated endocytosis. Has both a membrane binding/bending activity and the ability to recruit proteins essential to the formation of functional clathrin-coated pits. Has a lipid-binding activity with a preference for membranes enriched in phosphatidylserine and phosphoinositides (Pi(4,5) biphosphate) like the plasma membrane. Its membrane-bending activity might be important for the subsequent action of clathrin and adaptors in the formation of clathrin-coated vesicles. Involved in adaptor protein complex AP- 2-dependent endocytosis of the transferin receptor, it also functions in the AP-2-independent endocytosis of the LDL receptor.
| Catalog no. | 产品 | 适用 | 宿主 / 克隆类型 | 应用 | 价格和交货时间 |
|---|---|---|---|---|---|
| FCHO2 抗体 (AA 100-203) | 人, 小鼠 | 兔 Polyclonal |
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| FCHO2 抗体 | 人, 小鼠 | 兔 Polyclonal |
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Primary Antibody
- WB (Western Blotting: 所列应用)
- ELISA (ELISA: 所列应用)
- IF/ICC (Immunofluorescence (fixed cells): 所列应用)
- 适用
- 人, 小鼠
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- AA 100-203
Latest Publications for our FCHO2 抗体
: "A nanobody-based molecular toolkit provides new mechanistic insight into clathrin-coat initiation." in: eLife, Vol. 8, (2019) (PubMed).
: "Endocytic proteins are partitioned at the edge of the clathrin lattice in mammalian cells." in: Nature cell biology, Vol. 19, Issue 4, pp. 352-361, (2017) (PubMed).
: "Endocytic proteins are partitioned at the edge of the clathrin lattice in mammalian cells." in: Nature cell biology, Vol. 19, Issue 4, pp. 352-361, (2017) (PubMed).
Aliases for FCHO2 抗体
FCH domain only 2 (FCHO2) 抗体FCH domain only 2 (fcho2) 抗体
FCH domain only 2 (Fcho2) 抗体
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