F12 抗体
(Coagulation Factor XII (F12))
This gene encodes coagulation factor XII which circulates in blood as a zymogen. This single chain zymogen is converted to a two-chain serine protease with an heavy chain (alpha-factor XIIa) and a light chain. The heavy chain contains two fibronectin-type domains, two epidermal growth factor (EGF)-like domains, a kringle domain and a proline-rich domain, whereas the light chain contains only a catalytic domain. On activation, further cleavages takes place in the heavy chain, resulting in the production of beta-factor XIIa light chain and the alpha-factor XIIa light chain becomes beta-factor XIIa heavy chain. Prekallikrein is cleaved by factor XII to form kallikrein, which then cleaves factor XII first to alpha-factor XIIa and then to beta-factor XIIa. The active factor XIIa participates in the initiation of blood coagulation, fibrinolysis, and the generation of bradykinin and angiotensin. It activates coagulation factors VII and XI. Defects in this gene do not cause any clinical symptoms and the sole effect is that whole-blood clotting time is prolonged. [provided by RefSeq, Jul 2008].
recommended
recommended
recommended
F12 抗体 by 适用
Find F12 抗体 for a variety of species such as anti-Human F12, anti-Mouse F12, anti-Rat F12. The species listed below are among those available. Click on a link to go to the corresponding products.
F12 抗体 by 抗体来源
Find F12 抗体 with a specific 抗体来源. The 抗体来源 listed below are among those available. Click on a link to go to the corresponding products.
F12 抗体 by 克隆形成能力
Find available monoclonal or polyclonal F12 抗体. Click on a link to go to the corresponding products.
F12 抗体 by 克隆
Find F12 抗体 with a specific 克隆. The 克隆 listed below are among those available. Click on a link to go to the corresponding products.
F12 抗体 by 标记
Find F12 抗体 with a specific conjugate such as Biotin, FITC, HRP. The conjugates listed below are among those available. Click on a link to go to the corresponding products.
Popular F12 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IHC, IP, ICC
Validations
- (3)
Cat. No.
ABIN7432373
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Mouse
Application
WB, IHC, IP, ICC
Validations
- (3)
Cat. No.
ABIN7432376
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, PLA
Validations
- (3)
Cat. No.
ABIN560829
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
ELISA, IHC, IP, IHC (p), IEP
Validations
- (3)
Cat. No.
ABIN364435
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human, Rat
Application
WB, ELISA, IHC, ICC, IF
Validations
- (3)
Cat. No.
ABIN6261640
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA
Validations
- (1)
Cat. No.
ABIN7186683
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
ELISA, IHC
Validations
- (1)
Cat. No.
ABIN7147997
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB
Validations
- (1)
Cat. No.
ABIN6218787
Quantity
20 μL
Datasheet
Datasheet
Reactivity
Human
Application
IP, IEP
Validations
- (1)
Cat. No.
ABIN458009
Quantity
1 mL
Datasheet
Datasheet
Reactivity
Human, Mouse
Application
WB
Validations
- (1)
Cat. No.
ABIN7259454
Quantity
200 μL
Datasheet
Datasheet
Reactivity
Human, Monkey
Application
WB
Validations
- (1)
Cat. No.
ABIN6741747
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC
Validations
- (2)
Cat. No.
ABIN1853534
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse
Application
WB, IHC
Validations
- (2)
Cat. No.
ABIN7303398
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
ELISA, IP, IHC (p)
Validations
- (2)
Cat. No.
ABIN1734212
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human
Application
IP, IHC (p), EIA
Validations
- (2)
Cat. No.
ABIN614924
Quantity
50 μg
Datasheet
Datasheet
Latest Publications for our F12 抗体
: "Neutralizing blood-borne polyphosphate in vivo provides safe thromboprotection." in: Nature communications, Vol. 7, pp. 12616, (2018) (PubMed).: "Variance decomposition of protein profiles from antibody arrays using a longitudinal twin model." in: Proteome science, Vol. 9, pp. 73, (2011) (PubMed).
Aliases for F12 抗体
coagulation factor XII (F12) 抗体coagulation factor XII (Hageman factor) (F12) 抗体
FXII 抗体
HAE3 抗体
HAEX 抗体
HAF 抗体
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