FAS 抗体
(TNF Receptor Superfamily, Member 6 (FAS))
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor contains a death domain. It has been shown to play a central role in the physiological regulation of programmed cell death, and has been implicated in the pathogenesis of various malignancies and diseases of the immune system. The interaction of this receptor with its ligand allows the formation of a death-inducing signaling complex that includes Fas-associated death domain protein (FADD), caspase 8, and caspase 10. The autoproteolytic processing of the caspases in the complex triggers a downstream caspase cascade, and leads to apoptosis. This receptor has been also shown to activate NF-kappaB, MAPK3/ERK1, and MAPK8/JNK, and is found to be involved in transducing the proliferating signals in normal diploid fibroblast and T cells. Several alternatively spliced transcript variants have been described, some of which are candidates for nonsense-mediated mRNA decay (NMD). The isoforms lacking the transmembrane domain may negatively regulate the apoptosis mediated by the full length isoform. [provided by RefSeq, Mar 2011].
recommended
recommended
recommended
FAS 抗体 by Grade
Find FAS 抗体 with a specific Grade. The Grade listed below are among those available. Click on a link to go to the corresponding products.
FAS 抗体 by 抗体来源
Find FAS 抗体 with a specific 抗体来源. The 抗体来源 listed below are among those available. Click on a link to go to the corresponding products.
FAS 抗体 by 克隆形成能力
Find available monoclonal or polyclonal FAS 抗体. Click on a link to go to the corresponding products.
Popular FAS 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
ICC, FACS, ELISA, WB
Validations
- (2)
- (5)
Cat. No.
ABIN969518
Quantity
0.1 mg
Datasheet
Datasheet
Reactivity
Human
Application
WB
Validations
- (4)
- (5)
Cat. No.
ABIN3020739
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Mouse, Rat
Application
IHC (fro), IHC (p), WB
Validations
- (19)
- (4)
Cat. No.
ABIN3044338
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
IF, ELISA, WB
Validations
- (5)
Cat. No.
ABIN3030902
Quantity
0.4 mL
Datasheet
Datasheet
Reactivity
Human
Application
IF, WB
Validations
- (2)
- (3)
Cat. No.
ABIN652469
Quantity
400 μL
Datasheet
Datasheet
Reactivity
Human
Application
Coat, ELISA, FACS, IF, IHC, StM
Validations
- (4)
Cat. No.
ABIN6939781
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
IHC, WB
Validations
- (4)
Cat. No.
ABIN7254813
Quantity
200 μL
Datasheet
Datasheet
Reactivity
Human
Application
PLA, ELISA, WB
Validations
- (4)
Cat. No.
ABIN559907
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
IP, ELISA, WB
Validations
- (4)
Cat. No.
ABIN513442
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
IP, ELISA, WB
Validations
- (4)
Cat. No.
ABIN513435
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human
Application
FACS, IHC (p)
Validations
- (1)
- (2)
Cat. No.
ABIN94249
Quantity
100 tests
Datasheet
Datasheet
Reactivity
Human, Monkey, Mouse, Rat
Application
ELISA, FACS, IF (cc), IF (p), IHC (fro), IHC (p), WB
Validations
- (3)
- (2)
Cat. No.
ABIN726395
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
ELISA, IHC, WB
Validations
- (3)
Cat. No.
ABIN7127483
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
ELISA, ICC, IF, IHC, WB
Validations
- (1)
- (2)
Cat. No.
ABIN6261680
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
IHC, WB
Validations
- (4)
- (2)
Cat. No.
ABIN1944804
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our FAS 抗体
: "EGF-mediated reduced miR-92a-1-5p controls HTR-8/SVneo cell invasion through activation of MAPK8 and FAS which in turn increase MMP-2/-9 expression." in: Scientific reports, Vol. 10, Issue 1, pp. 12274, (2020) (PubMed).: "Dietary methionine restriction reduces hepatic steatosis and oxidative stress in high-fat-fed mice by promoting H2S production." in: Food & function, Vol. 10, Issue 1, pp. 61-77, (2019) (PubMed).
: "Danshensu Decreases UVB-Induced Corneal Inflammation in an Experimental Mouse Model via Oral Administration." in: Current eye research, Vol. 43, Issue 1, pp. 27-34, (2018) (PubMed).
: "Artesunate enhances γδ T-cell-mediated antitumor activity through augmenting γδ T-cell function and reversing immune escape of HepG2 cells." in: Immunopharmacology and immunotoxicology, Vol. 40, Issue 2, pp. 107-116, (2018) (PubMed).
: "Regulation of fibroblast Fas expression by soluble and mechanical pro-fibrotic stimuli." in: Respiratory research, Vol. 19, Issue 1, pp. 91, (2018) (PubMed).
: "Prior Puma Lentivirus Infection Modifies Early Immune Responses and Attenuates Feline Immunodeficiency Virus Infection in Cats." in: Viruses, Vol. 10, Issue 4, (2018) (PubMed).
: "SUMO2 modification of Aurora B and its impact on follicular development and atresia in the mouse ovary." in: International journal of molecular medicine, Vol. 41, Issue 6, pp. 3115-3126, (2018) (PubMed).
: "Inflammatory signature of cerebellar neurodegeneration during neonatal hyperbilirubinemia in Ugt1 (-/-) mouse model." in: Journal of neuroinflammation, Vol. 14, Issue 1, pp. 64, (2017) (PubMed).
: "The Utility of Biomarkers in Osteoporosis Management." in: Molecular diagnosis & therapy, Vol. 21, Issue 4, pp. 401-418, (2017) (PubMed).
: "BRE modulates granulosa cell death to affect ovarian follicle development and atresia in the mouse." in: Cell death & disease, Vol. 8, Issue 3, pp. e2697, (2017) (PubMed).
Aliases for FAS 抗体
Fas cell surface death receptor (FAS) 抗体Fas ligand (FASLG) 抗体
Fas ligand (TNF superfamily, member 6) (Fasl) 抗体
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta (YWHAZ) 抗体
Fas (TNF receptor superfamily member 6) (Fas) 抗体
Fas cell surface death receptor (Fas) 抗体
Fas cell surface death receptor (fas) 抗体
AI196731 抗体
ALPS1A 抗体
APO-1 抗体
APO1 抗体
APT1 抗体
APT1LG1 抗体
CD95 抗体
CD95-L 抗体
CD95L 抗体
CD178 抗体
Fas-L 抗体
FAS1 抗体
FASL 抗体
Faslg 抗体
FASTM 抗体
gld 抗体
lpr 抗体
TNFR6 抗体
TNFRSF6 抗体
Tnfrsf6 抗体
TNFSF6 抗体
Tnfsf6 抗体
您还需要查找其他产品吗？
You are here:
