Aminoacyl-tRNA synthetases are a class of enzymes that charge tRNAs with their cognate amino acids. The protein encoded by this gene is a multifunctional aminoacyl-tRNA synthetase that catalyzes the aminoacylation of glutamic acid and proline tRNA species. Alternative splicing has been observed for this gene, but the full-length nature and biological validity of the variant have not been determined. [provided by RefSeq, Jul 2008].
Jia, Arif, Ray, Fox: "WHEP domains direct noncanonical function of glutamyl-Prolyl tRNA synthetase in translational control of gene expression." in: Molecular cell, Vol. 29, Issue 6, pp. 679-90, (2008) (PubMed).
Beausoleil, Villén, Gerber, Rush, Gygi: "A probability-based approach for high-throughput protein phosphorylation analysis and site localization." in: Nature biotechnology, Vol. 24, Issue 10, pp. 1285-92, (2006) (PubMed).
Kato, Daigo, Hayama, Ishikawa, Yamabuki, Ito, Miyamoto, Kondo, Nakamura: "A novel human tRNA-dihydrouridine synthase involved in pulmonary carcinogenesis." in: Cancer research, Vol. 65, Issue 13, pp. 5638-46, (2005) (PubMed).