EIF2AK2 抗体
(Eukaryotic Translation Initiation Factor 2-alpha Kinase 2 (EIF2AK2))
The protein encoded by this gene is a serine/threonine protein kinase that is activated by autophosphorylation after binding to dsRNA. The activated form of the encoded protein can phosphorylate translation initiation factor EIF2S1, which in turn inhibits protein synthesis. This protein is also activated by manganese ions and heparin. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Oct 2011].
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148 results
EIF2AK2
适用: 人, 小鼠, 大鼠
WB, IHC (p), FACS
宿主: 兔
Monoclonal
10A1
unconjugated
1 image
Latest Publications for our EIF2AK2 抗体
: "PKR kinase directly regulates tau expression and Alzheimer's disease-related tau phosphorylation." in: Brain pathology (Zurich, Switzerland), (2020) (PubMed).: "PKR regulates proliferation, differentiation, and survival of murine hematopoietic stem/progenitor cells." in: Blood, Vol. 121, Issue 17, pp. 3364-74, (2013) (PubMed).
: "PKR negatively regulates leukemia progression in association with PP2A activation, Bcl-2 inhibition and increased apoptosis." in: Blood cancer journal, Vol. 3, pp. e144, (2013) (PubMed).
: "Signaling dynamics of palmitate-induced ER stress responses mediated by ATF4 in HepG2 cells." in: BMC systems biology, Vol. 7, pp. 9, (2013) (PubMed).
: "Increased expression of the dsRNA-activated protein kinase PKR in breast cancer promotes sensitivity to doxorubicin." in: PLoS ONE, Vol. 7, Issue 9, pp. e46040, (2012) (PubMed).
: "Airborne particulate matter selectively activates endoplasmic reticulum stress response in the lung and liver tissues." in: American journal of physiology. Cell physiology, Vol. 299, Issue 4, pp. C736-49, (2010) (PubMed).
: "Human gene profiling in response to the active protein kinase, interferon-induced serine/threonine protein kinase (PKR), in infected cells. Involvement of the transcription factor ATF-3 IN ..." in: The Journal of biological chemistry, Vol. 281, Issue 27, pp. 18734-45, (2006) (PubMed).
: "Sindbis virus translation is inhibited by a PKR/RNase L-independent effector induced by alpha/beta interferon priming of dendritic cells." in: Journal of virology, Vol. 79, Issue 3, pp. 1487-99, (2005) (PubMed).
: "The Fanconi anemia proteins functionally interact with the protein kinase regulated by RNA (PKR)." in: The Journal of biological chemistry, Vol. 279, Issue 42, pp. 43910-9, (2004) (PubMed).
: "PKR gene expression and response to pegylated interferon plus ribavirin therapy in chronic hepatitis C." in: Antiviral therapy, Vol. 9, Issue 5, pp. 763-70, (2004) (PubMed).
Aliases for EIF2AK2 抗体
eukaryotic translation initiation factor 2 alpha kinase 2 (EIF2AK2) 抗体eukaryotic translation initiation factor 2-alpha kinase 2 (eif2ak2) 抗体
eukaryotic translation initiation factor 2-alpha kinase 2 (Eif2ak2) 抗体
2310047A08Rik 抗体
4732414G15Rik 抗体
AI467567 抗体
AI747578 抗体
DKFZp469K1934 抗体
EIF2AK1 抗体
EIF2AK2 抗体
PKR 抗体
pkr 抗体
Pkr 抗体
PRKR 抗体
Prkr 抗体
Tik 抗体
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