EIF2AK2 抗体 (Middle Region)
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北京 101111
Quick Overview for EIF2AK2 抗体 (Middle Region) (ABIN2774645)
抗原
See all EIF2AK2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Middle Region
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原理
- EIF2AK2 Antibody - middle region
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序列
- QVFKAKHRID GKTYVIKRVK YNNEKAEREV KALAKLDHVN IVHYNGCWDG
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预测反应
- Cow: 92%, Dog: 83%, Horse: 91%, Human: 100%, Mouse: 83%, Pig: 83%, Rabbit: 100%, Rat: 92%
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产品特性
- This is a rabbit polyclonal antibody against EIF2AK2. It was validated on Western Blot.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human EIF2AK2
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应用备注
- Optimal working dilution should be determined by the investigator.
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说明
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We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP36709-100UG
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.5 mg/mL
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缓冲液
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- prevent freeze-thaw cycles
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储存条件
- 4 °C,-20 °C
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储存方法
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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- EIF2AK2 (Eukaryotic Translation Initiation Factor 2-alpha Kinase 2 (EIF2AK2))
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别名
- EIF2AK2
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背景
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Background Information: EIF2AK2 might play a role in ER stress-induced apoptosis and in Alzheimer's disease. Alzheimer cases show prominent EIF2AK2 activation in association with neuritic plaques and pyramidal neurons in the hippocampus and neocortex.
Gene Name: Eukaryotic translation initiation factor 2-alpha kinase 2
Alternative Symbols: PKR, PRKR, LEUDEN, EIF2AK1, PPP1R83
Protein Name: Interferon-induced, double-stranded RNA-activated protein kinase
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分子量
- 62kDa
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基因ID
- 5610
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NCBI登录号
- NP_002750
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UniProt
- P19525
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途径
- DNA Damage Repair, ER-Nucleus Signaling, Hepatitis C
抗原
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