EGFR 蛋白
(Epidermal Growth Factor Receptor (EGFR))
The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer. Multiple alternatively spliced transcript variants that encode different protein isoforms have been found for this gene. [provided by RefSeq, Jul 2010].
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73 results
EGFR
宿主: 人
宿主: HEK-293 Cells
Recombinant
>95 % as determined by SDS-PAGE.
Func
Active
EGFR
宿主: 人
宿主: HEK-293 Cells
Recombinant
>95 % as determined by SDS-PAGE.
Active
EGFR
宿主: 人
宿主: 大肠杆菌（E. Coli）
Recombinant
> 80 % as determined by reducing SDS-PAGE.
Imm
EGFR
宿主: 人
宿主: Insect Cells
Recombinant
~ 90 % by SDS-PAGE
Active
EGFR
宿主: 人
宿主: Insect cells (Sf9)
Recombinant
> 95 % by SDS-PAGE and HPLC analyses.
EGFR
宿主: 人
宿主: CHO Cells
Recombinant
> 95 % as analyzed by SDS-PAGE.
Active
EGFR
宿主: 人
宿主: 人细胞
Recombinant
> 95 % as determined by reducing SDS-PAGE.
Active
EGFR
宿主: 人
宿主: Insect Cells
Recombinant
~ 90 % by SDS-PAGE. Visualized by silver stain
EGFR
宿主: 人
宿主: 人细胞
Recombinant
> 95 % as determined by reducing SDS-PAGE.
EGFR
宿主: 人
宿主: 人细胞
Recombinant
> 95 % as determined by reducing SDS-PAGE.
EGFR
宿主: 人
宿主: HEK-293 Cells
Recombinant
The purity of the protein is greater than 85 % as determined by SDS-PAGE and Coomassie blue staining.
EGFR
宿主: 人
宿主: HEK-293 Cells
Recombinant
The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
EGFR
宿主: 人
宿主: HEK-293 Cells
Recombinant
> 97 % as determined by reducing SDS-PAGE.
Active
EGFR
宿主: 人
宿主: 大肠杆菌（E. Coli）
Recombinant
> 90 %
WB, SDS, Imm, PC
EGFR
宿主: 人
宿主: 大肠杆菌（E. Coli）
Recombinant
> 80 %
WB, SDS, Imm, PC
Latest Publications for our EGFR 蛋白
: "A Cell-free Expression Pipeline for the Generation and Functional Characterization of Nanobodies." in: Frontiers in bioengineering and biotechnology, Vol. 10, pp. 896763, (2022) (PubMed).: "Constructive approach for synthesis of a functional IgG using a reconstituted cell-free protein synthesis system." in: Scientific reports, Vol. 9, Issue 1, pp. 671, (2020) (PubMed).
: "Enhancing T cell therapy through TCR-signaling-responsive nanoparticle drug delivery." in: Nature biotechnology, Vol. 36, Issue 8, pp. 707-716, (2019) (PubMed).
: "Small-Molecule Probes for Affinity-Guided Introduction of Biocompatible Handles on Metal-Binding Proteins." in: Bioconjugate chemistry, Vol. 29, Issue 9, pp. 3016-3025, (2019) (PubMed).
: "An EGFR-targeting antibody-drug conjugate LR004-VC-MMAE: potential in esophageal squamous cell carcinoma and other malignancies." in: Molecular oncology, Vol. 13, Issue 2, pp. 246-263, (2019) (PubMed).
: "CAR-T cells secreting BiTEs circumvent antigen escape without detectable toxicity." in: Nature biotechnology, (2019) (PubMed).
: "Plasma-Generated OH Radical Production for Analyzing Three-Dimensional Structure in Protein Therapeutics." in: Scientific reports, Vol. 7, Issue 1, pp. 12946, (2019) (PubMed).
: "Mabfilin and Fabfilin - New antibody-scaffold fusion formats for multispecific targeting concepts." in: Protein expression and purification, Vol. 149, pp. 51-65, (2018) (PubMed).
: "AllergoOncology: Generating a canine anticancer IgE against the epidermal growth factor receptor." in: The Journal of allergy and clinical immunology, Vol. 142, Issue 3, pp. 973-976.e11, (2018) (PubMed).
: "Intramolecular trimerization, a novel strategy for making multispecific antibodies with controlled orientation of the antigen binding domains." in: Scientific reports, Vol. 6, pp. 28643, (2018) (PubMed).
Aliases for EGFR 蛋白
epidermal growth factor receptor (EGFR) 蛋白Epidermal growth factor receptor (Egfr) 蛋白
epidermal growth factor receptor a (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian) (egfra) 蛋白
epidermal growth factor receptor (egfr1) 蛋白
epidermal growth factor receptor (LOC5564544) 蛋白
epidermal growth factor receptor (Egfr) 蛋白
9030024J15Rik 蛋白
AI552599 蛋白
C-erb 蛋白
c-erbB 蛋白
CG10079 蛋白
D-Egf 蛋白
d-egf-r 蛋白
D-EGFR 蛋白
DEGFR 蛋白
DEgfr 蛋白
Degfr 蛋白
dEGFR 蛋白
dEgfr 蛋白
dEGFR1 蛋白
DER 蛋白
Der 蛋白
der 蛋白
DER/EGFR 蛋白
DER/faint little ball 蛋白
DER/top 蛋白
DER/torpedo 蛋白
DER1 蛋白
DER flb 蛋白
Dmel\\CG10079 蛋白
DmHD-33 蛋白
EFG-R 蛋白
Egf 蛋白
EGF-R 蛋白
Egf-r 蛋白
EGFR 蛋白
EGFr 蛋白
EGfr 蛋白
EgfR 蛋白
egfr 蛋白
egfr1 蛋白
EGFR12 蛋白
EGFR15 蛋白
EK2-6 蛋白
El 蛋白
Elp 蛋白
Elp-1 蛋白
Elp-B1 蛋白
Elp-B1RB1 蛋白
ERBB 蛋白
Erbb 蛋白
ErbB-1 蛋白
ERBB1 蛋白
Erbb2 蛋白
Errb1 蛋白
Errp 蛋白
flb 蛋白
HD-33 蛋白
HER1 蛋白
l(2)05351 蛋白
l(2)09261 蛋白
l(2)57DEFa 蛋白
l(2)57Ea 蛋白
l(2)57EFa 蛋白
mENA 蛋白
mor1 蛋白
PIG61 蛋白
TOP 蛋白
top 蛋白
top/DER 蛋白
top/flb 蛋白
Torpedo/DER 蛋白
Torpedo/Egfr 蛋白
torpedo/Egfr 蛋白
torpedo/egfr 蛋白
wa-2 蛋白
wa2 蛋白
Wa5 蛋白
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