E3 SUMO-Protein Ligase NSE2 抗体
(E3 SUMO-Protein Ligase NSE2 (NSMCE2))
E3 SUMO-protein ligase component of the SMC5-SMC6 complex, a complex involved in repair of DNA double-strand breaks by homologous recombination. Is not be required for the stability of the complex.The complex may promote sister chromatid homologous recombination by recruiting the SMC1-SMC3 cohesin complex to double-strand breaks. The complex is required for telomere maintenance via recombination and mediates sumoylation of shelterin complex (telosome) components. Acts as a E3 ligase mediating SUMO attachment to various proteins such as SMC6L1 and TRAX, the shelterin complex subunits TERF1, TERF2, TINF2 and TERF2IP, and maybe the cohesin components RAD21 and STAG2. Required for recruitment of telomeres to PML nuclear bodies. SUMO protein-ligase activity is required for the prevention of DNA damage-induced apoptosis by facilitating DNA repair. Required for sister chromatid cohesion during prometaphase and mitotic progression (By similarity).
| Catalog no. | 产品 | 适用 | 宿主 / 克隆类型 | 应用 | 价格和交货时间 |
|---|---|---|---|---|---|
| NSMCE2 抗体 (Alexa Fluor 750) | 人 | 兔 Polyclonal |
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| NSMCE2 抗体 (Alexa Fluor 555) | 人 | 兔 Polyclonal |
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| NSMCE2 抗体 (Alexa Fluor 680) | 人 | 兔 Polyclonal |
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| NSMCE2 抗体 (Center) | 人, 小鼠, 大鼠 | 兔 Polyclonal |
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| NSMCE2 抗体 (AA 14-228) | 人 | 兔 Polyclonal |
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| NSMCE2 抗体 (Alexa Fluor 488) | 人 | 兔 Polyclonal |
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| NSMCE2 抗体 (Alexa Fluor 594) | 人 | 兔 Polyclonal |
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| NSMCE2 抗体 (Alexa Fluor 750) | 人 | 兔 Polyclonal |
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| NSMCE2 抗体 (Alexa Fluor 680) | 人 | 兔 Polyclonal |
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| NSMCE2 抗体 (Alexa Fluor 555) | 人 | 兔 Polyclonal |
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| NSMCE2 抗体 (Alexa Fluor 647) | 人 | 兔 Polyclonal |
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Primary Antibody
- WB (Western Blotting: 所列应用)
- 适用
- 人, 小鼠, 大鼠
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗原表位
- Center
Primary Antibody
- WB (Western Blotting: 所列应用)
- ELISA (ELISA: 所列应用)
- IF (Immunofluorescence: 所列应用)
- FACS (Flow Cytometry: 所列应用)
- IP (Immunoprecipitation: 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- AA 14-228
Latest Publications for our E3 SUMO-Protein Ligase NSE2 抗体
: "Non-SMC Element 2 (NSMCE2) of the SMC5/6 Complex Helps to Resolve Topological Stress." in: International journal of molecular sciences, Vol. 17, Issue 11, (2016) (PubMed).
: "Expulsion of micronuclei containing amplified genes contributes to a decrease in double minute chromosomes from malignant tumor cells." in: International journal of cancer. Journal international du cancer, Vol. 134, Issue 6, pp. 1279-88, (2014) (PubMed).
: "De novo assembly of a PML nuclear subcompartment occurs through multiple pathways and induces telomere elongation." in: Journal of cell science, Vol. 124, Issue Pt 21, pp. 3603-18, (2011) (PubMed).
: "Expulsion of micronuclei containing amplified genes contributes to a decrease in double minute chromosomes from malignant tumor cells." in: International journal of cancer. Journal international du cancer, Vol. 134, Issue 6, pp. 1279-88, (2014) (PubMed).
: "De novo assembly of a PML nuclear subcompartment occurs through multiple pathways and induces telomere elongation." in: Journal of cell science, Vol. 124, Issue Pt 21, pp. 3603-18, (2011) (PubMed).
Aliases for E3 SUMO-Protein Ligase NSE2 抗体
family with sequence similarity 84 member B (FAM84B) 抗体NSE2/MMS21 homolog, SMC5-SMC6 complex SUMO ligase (Nsmce2) 抗体
NSE2/MMS21 homolog, SMC5-SMC6 complex SUMO ligase (NSMCE2) 抗体
NSE2/MMS21 homolog, SMC5-SMC6 complex SUMO ligase L homeolog (nsmce2.L) 抗体
Smc5-6 complex non-SMC subunit 2 (nse2) 抗体
family with sequence similarity 84, member B (Fam84b) 抗体
family with sequence similarity 84, member B (fam84b) 抗体
1110014D18Rik 抗体
AI661537 抗体
BCMP101 抗体
BF642811 抗体
C8orf36 抗体
D330050I23Rik 抗体
MMS21 抗体
Non-SMC element 2 抗体
NSE2 抗体
RGD1305156 抗体
si:dkey-5e12.3 抗体
zgc:153371 抗体
ZMIZ7 抗体
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