NSMCE2 抗体 (AA 14-228)
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Quick Overview for NSMCE2 抗体 (AA 14-228) (ABIN7870621)
抗原
See all NSMCE2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 14-228
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原理
- NSMCE2 Antibody / NSE2 / MMS21
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纯化方法
- Antigen affinity purified
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免疫原
- An E.coli-derived human recombinant protein (F14-D228) was used as the immunogen for the NSMCE2 antibody.
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亚型
- IgG
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应用备注
- Optimal dilution of the NSMCE2 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the NSMCE2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- NSMCE2 (E3 SUMO-Protein Ligase NSE2 (NSMCE2))
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别名
- NSMCE2
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背景
- This gene encodes a member of a family of E3 small ubiquitin-related modifier (SUMO) ligases that mediates the attachment of a SUMO protein to proteins involved in nuclear transport, transcription, chromosome segregation and DNA repair. The encoded protein is part of the structural maintenance of chromosomes (SMC) 5/6 complex which plays a key role genome maintenance, facilitating chromosome segregation and suppressing mitotic recombination. A knockout of the orthologous mouse gene is lethal prior to embryonic day 10.5. Naturally occurring mutations in this gene, that abolish the SUMO ligase activity, are associated with primordial dwarfism and extreme insulin resistance.
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UniProt
- Q96MF7
抗原
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