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DYRK1A 抗体

(Dual-Specificity tyrosine-(Y)-phosphorylation Regulated Kinase 1A (DYRK1A))
This gene encodes a member of the Dual-specificity tyrosine phosphorylation-regulated kinase (DYRK) family. This member contains a nuclear targeting signal sequence, a protein kinase domain, a leucine zipper motif, and a highly conservative 13-consecutive-histidine repeat. It catalyzes its autophosphorylation on serine/threonine and tyrosine residues. It may play a significant role in a signaling pathway regulating cell proliferation and may be involved in brain development. This gene is a homolog of Drosophila mnb (minibrain) gene and rat Dyrk gene. It is localized in the Down syndrome critical region of chromosome 21, and is considered to be a strong candidate gene for learning defects associated with Down syndrome. Alternative splicing of this gene generates several transcript variants differing from each other either in the 5' UTR or in the 3' coding region. These variants encode at least five different isoforms. [provided by RefSeq, Jul 2008].
DYRK1A 抗体  (AA 674-763) DYRK1A 抗体  (AA 674-763) DYRK1A 抗体 (AA 674-763) (ABIN560675)

DYRK1A 适用: 人 ELISA, WB 宿主: 小鼠 Monoclonal 7D10 unconjugated

DYRK1A 抗体  (N-Term) DYRK1A 抗体  (N-Term) DYRK1A 抗体 (N-Term) (ABIN6257024)

DYRK1A 适用: 人, 小鼠, 大鼠 ELISA, ICC, IF, WB 宿主: 兔 Polyclonal unconjugated

DYRK1A 抗体  (N-Term) DYRK1A 抗体  (N-Term) DYRK1A 抗体 (N-Term) (ABIN2707485)

DYRK1A 适用: 人, 大鼠, 兔 IC, IF, IHC, WB 宿主: 兔 Polyclonal unconjugated

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Find DYRK1A 抗体 for a variety of species such as anti-Human DYRK1A, anti-Mouse DYRK1A, anti-Rat DYRK1A. The species listed below are among those available. Click on a link to go to the corresponding products.

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Popular DYRK1A 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Mouse
Application IHC, ELISA, WB
Validations
  • (3)
Cat. No. ABIN3030777
Quantity 0.4 mL
Datasheet Datasheet
Reactivity Human
Application ELISA, IF, IHC, WB
Validations
  • (2)
Cat. No. ABIN7188711
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application ELISA, IF, IHC (p), WB
Validations
  • (2)
Cat. No. ABIN7214642
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application ELISA, IF, IHC, WB
Validations
  • (2)
Cat. No. ABIN3184371
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application ELISA, IP, WB
Validations
  • (2)
  • (1)
Cat. No. ABIN5539713
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application IF, ELISA, WB
Validations
  • (2)
Cat. No. ABIN1533878
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse
Application ELISA, WB
Validations
  • (2)
Cat. No. ABIN3028627
Quantity 0.4 mL
Datasheet Datasheet
Reactivity Bat, Cow, Guinea Pig, Horse, Human, Monkey, Mouse, Pig, Rabbit, Rat
Application IHC, IHC (p), WB
Validations
  • (2)
Cat. No. ABIN769026
Quantity 50 μg
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application ELISA, WB
Validations
  • (1)
Cat. No. ABIN5693108
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse
Application WB
Validations
  • (4)
Cat. No. ABIN1881275
Quantity 400 μL
Datasheet Datasheet
Reactivity Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat, Zebrafish (Danio rerio)
Application WB
Validations
  • (1)
Cat. No. ABIN2782363
Quantity 100 μL
Datasheet Datasheet

Application WB
Validations
  • (1)
Cat. No. ABIN6743391
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application IP, IHC, WB
Validations
  • (1)
Cat. No. ABIN297140
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application IP, WB
Validations
  • (1)
Cat. No. ABIN264978
Quantity 0.1 mg
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application EIA, WB
Validations
  • (1)
Cat. No. ABIN783434
Quantity 0.1 mg
Datasheet Datasheet

Latest Publications for our DYRK1A 抗体

Widowati, Bamberg-Lemper, Becker: "Mutational analysis of two residues in the DYRK homology box of the protein kinase DYRK1A." in: BMC research notes, Vol. 11, Issue 1, pp. 297, (2018) (PubMed).

Widowati, Ernst, Hausmann, Müller-Newen, Becker: "Functional characterization of DYRK1A missense variants associated with a syndromic form of intellectual deficiency and autism." in: Biology open, Vol. 7, Issue 4, (2018) (PubMed).

Rabaneda, Geribaldi-Doldán, Murillo-Carretero, Carrasco, Martínez-Salas, Verástegui, Castro: "Altered regulation of the Spry2/Dyrk1A/PP2A triad by homocysteine impairs neural progenitor cell proliferation." in: Biochimica et biophysica acta, Vol. 1863, Issue 12, pp. 3015-3026, (2016) (PubMed).

Souchet, Latour, Gu, Daubigney, Paul, Delabar, Janel: "Molecular rescue of DYRK1A overexpression in cystathionine beta synthase-deficient mouse brain by enriched environment combined with voluntary exercise." in: Journal of molecular neuroscience : MN, Vol. 55, Issue 2, pp. 318-23, (2015) (PubMed).

Thompson, Bhansali, Diebold, Cook, Stolzenburg, Casagrande, Besson, Leblond, Désiré, Malinge, Crispino: "DYRK1A controls the transition from proliferation to quiescence during lymphoid development by destabilizing Cyclin D3." in: The Journal of experimental medicine, Vol. 212, Issue 6, pp. 953-70, (2015) (PubMed).

Najas, Arranz, Lochhead, Ashford, Oxley, Delabar, Cook, Barallobre, Arbonés: "DYRK1A-mediated Cyclin D1 Degradation in Neural Stem Cells Contributes to the Neurogenic Cortical Defects in Down Syndrome." in: EBioMedicine, Vol. 2, Issue 2, pp. 120-34, (2015) (PubMed).

Blazek, Abeysekera, Li, Roper: "Rescue of the abnormal skeletal phenotype in Ts65Dn Down syndrome mice using genetic and therapeutic modulation of trisomic Dyrk1a." in: Human molecular genetics, Vol. 24, Issue 20, pp. 5687-96, (2015) (PubMed).

Stringer, Abeysekera, Dria, Roper, Goodlett: "Low dose EGCG treatment beginning in adolescence does not improve cognitive impairment in a Down syndrome mouse model." in: Pharmacology, biochemistry, and behavior, Vol. 138, pp. 70-9, (2015) (PubMed).

Fant, Durieu, Chicanne, Payrastre, Sbrissa, Shisheva, Limanton, Carreaux, Bazureau, Meijer: "cdc-like/dual-specificity tyrosine phosphorylation-regulated kinases inhibitor leucettine L41 induces mTOR-dependent autophagy: implication for Alzheimer's disease." in: Molecular pharmacology, Vol. 85, Issue 3, pp. 441-50, (2014) (PubMed).

Hibaoui, Grad, Letourneau, Sailani, Dahoun, Santoni, Gimelli, Guipponi, Pelte, Béna, Antonarakis, Feki: "Modelling and rescuing neurodevelopmental defect of Down syndrome using induced pluripotent stem cells from monozygotic twins discordant for trisomy 21." in: EMBO molecular medicine, Vol. 6, Issue 2, pp. 259-77, (2014) (PubMed).

Aliases for DYRK1A 抗体

dual specificity tyrosine phosphorylation regulated kinase 1A (DYRK1A) 抗体
dual specificity tyrosine-(Y)-phosphorylation regulated kinase 1A (dyrk1a) 抗体
dual specificity tyrosine phosphorylation regulated kinase 1A (dyrk1a) 抗体
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1a (Dyrk1a) 抗体
dual specificity tyrosine phosphorylation regulated kinase 1A (Dyrk1a) 抗体
dual specificity tyrosine-(Y)-phosphorylation regulated kinase 1A S homeolog (dyrk1a.S) 抗体
2310043O08Rik 抗体
D16Ertd272e 抗体
D16Ertd493e 抗体
dyrk 抗体
DYRK 抗体
Dyrk 抗体
dyrk1 抗体
DYRK1 抗体
DYRK1A 抗体
ENSMUSG00000074897 抗体
Gm10783 抗体
hp86 抗体
HP86 抗体
mmb 抗体
mnb 抗体
MNB 抗体
mnbh 抗体
MNBH 抗体
Mnbh 抗体
Mp86 抗体
MRD7 抗体
PSK47 抗体
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