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DYRK1A 抗体 (N-Term)

DYRK1A 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6257024
发货至: 中国
  • 抗原 See all DYRK1A 抗体
    DYRK1A (Dual-Specificity tyrosine-(Y)-phosphorylation Regulated Kinase 1A (DYRK1A))
    抗原表位
    • 15
    • 9
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    • 7
    • 5
    • 3
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    • 1
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    N-Term
    适用
    • 71
    • 30
    • 21
    • 6
    • 5
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    • 4
    • 4
    • 2
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    人, 小鼠, 大鼠
    宿主
    • 65
    • 4
    • 3
    • 1
    克隆类型
    • 69
    • 4
    多克隆
    标记
    • 37
    • 6
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    • 1
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    This DYRK1A antibody is un-conjugated
    应用范围
    • 73
    • 42
    • 13
    • 13
    • 13
    • 12
    • 6
    • 6
    • 4
    • 3
    • 2
    • 2
    • 1
    Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
    特异性
    DYR1A Antibody detects endogenous levels of total DYR1A.
    预测反应
    Pig,Bovine,Horse,Sheep,Dog,Chicken
    纯化方法
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    免疫原
    A synthesized peptide derived from human DYR1A, corresponding to a region within N-terminal amino acids.
    亚型
    IgG
    Top Product
    Discover our top product DYRK1A Primary Antibody
  • 应用备注
    WB 1:500-1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20 °C. Stable for 12 months from date of receipt.
    有效期
    12 months
  • 抗原
    DYRK1A (Dual-Specificity tyrosine-(Y)-phosphorylation Regulated Kinase 1A (DYRK1A))
    别名
    DYRK1A (DYRK1A 产品)
    别名
    DYRK1A antibody, dyrk antibody, dyrk1 antibody, hp86 antibody, mnb antibody, mnbh antibody, DYRK antibody, DYRK1 antibody, HP86 antibody, MNB antibody, MNBH antibody, MRD7 antibody, 2310043O08Rik antibody, D16Ertd272e antibody, D16Ertd493e antibody, Dyrk antibody, ENSMUSG00000074897 antibody, Gm10783 antibody, Mnbh antibody, Mp86 antibody, mmb antibody, PSK47 antibody, dual specificity tyrosine phosphorylation regulated kinase 1A antibody, dual specificity tyrosine-(Y)-phosphorylation regulated kinase 1A antibody, dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1a antibody, dual specificity tyrosine-(Y)-phosphorylation regulated kinase 1A S homeolog antibody, DYRK1A antibody, dyrk1a antibody, Dyrk1a antibody, dyrk1a.S antibody
    背景

    Description: Dual-specificity kinase which possesses both serine/threonine and tyrosine kinase activities. May play a role in a signaling pathway regulating nuclear functions of cell proliferation. Modulates alternative splicing by phosphorylating the splice factor SRSF6 (By similarity). Exhibits a substrate preference for proline at position P+1 and arginine at position P-3. Has pro-survival function and negatively regulates the apoptotic process. Promotes cell survival upon genotoxic stress through phosphorylation of SIRT1. This in turn inhibits TP53 activity and apoptosis (By similarity).

    Gene: DYRK1A

    分子量
    90 kDa
    基因ID
    1859
    UniProt
    Q13627
    途径
    Mitotic G1-G1/S Phases
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