Dynamitin 抗体
(Dynactin 2 (p50) (DCTN2))
This gene encodes a 50-kD subunit of dynactin, a macromolecular complex consisting of 10-11 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein. It is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, chromosome movement, nuclear positioning, and axonogenesis. This subunit is present in 4-5 copies per dynactin molecule. It contains three short alpha-helical coiled-coil domains that may mediate association with self or other dynactin subunits. It may interact directly with the largest subunit (p150) of dynactin and may affix p150 in place. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, May 2012].
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Find Dynamitin 抗体 for a variety of species such as anti-Human Dynamitin, anti-Mouse Dynamitin, anti-Rat Dynamitin. The species listed below are among those available. Click on a link to go to the corresponding products.
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Popular Dynamitin 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IF
Validations
- (1)
- (4)
Cat. No.
ABIN523956
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IF
Validations
- (4)
Cat. No.
ABIN564596
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
ELISA, IHC, IF
Validations
- (2)
Cat. No.
ABIN7150805
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, IP
Validations
- (2)
Cat. No.
ABIN1327253
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, ELISA, IF, ICC
Validations
- (2)
Cat. No.
ABIN6263969
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC
Validations
- (1)
Cat. No.
ABIN7184840
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, ELISA, IHC
Validations
- (1)
Cat. No.
ABIN3184368
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB
Validations
- (1)
Cat. No.
ABIN7266851
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC (p)
Validations
- (2)
Cat. No.
ABIN656819
Quantity
400 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC (p), EIA
Validations
- (2)
Cat. No.
ABIN952005
Quantity
0.4 mL
Datasheet
Datasheet
Reactivity
Mouse
Application
WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro)
Validations
Cat. No.
ABIN872902
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Mouse
Application
WB, ELISA, IHC (p), IHC (fro)
Validations
Cat. No.
ABIN894642
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Mouse
Application
WB, IF (cc), IF (p)
Validations
Cat. No.
ABIN894649
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Mouse
Application
WB, IF (cc), IF (p)
Validations
Cat. No.
ABIN894648
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Mouse
Application
WB, IF (cc), IF (p)
Validations
Cat. No.
ABIN894650
Quantity
100 μL
Datasheet
Datasheet
Latest Publications for our Dynamitin 抗体
: "Proteins that mediate protein aggregation and cytotoxicity distinguish Alzheimer's hippocampus from normal controls." in: Aging cell, Vol. 15, Issue 5, pp. 924-39, (2016) (PubMed).: "Integrin-linked kinase links dynactin-1/dynactin-2 with cortical integrin receptors to orient the mitotic spindle relative to the substratum." in: Scientific reports, Vol. 5, pp. 8389, (2015) (PubMed).
: "Dynamitin affects cell-surface expression of voltage-gated sodium channel Nav1.5." in: The Biochemical journal, Vol. 463, Issue 3, pp. 339-49, (2014) (PubMed).
: "Induction of human MDR1 gene expression by 2-acetylaminofluorene is mediated by effectors of the phosphoinositide 3-kinase pathway that activate NF-kappaB signaling." in: Oncogene, Vol. 21, Issue 13, pp. 1945-54, (2002) (PubMed).
: "beta III spectrin binds to the Arp1 subunit of dynactin." in: The Journal of biological chemistry, Vol. 276, Issue 39, pp. 36598-605, (2001) (PubMed).
: "ZW10 helps recruit dynactin and dynein to the kinetochore." in: The Journal of cell biology, Vol. 142, Issue 3, pp. 763-74, (1998) (PubMed).
: "Overexpression of the dynamitin (p50) subunit of the dynactin complex disrupts dynein-dependent maintenance of membrane organelle distribution." in: The Journal of cell biology, Vol. 139, Issue 2, pp. 469-84, (1997) (PubMed).
: "Molecular characterization of the 50-kD subunit of dynactin reveals function for the complex in chromosome alignment and spindle organization during mitosis." in: The Journal of cell biology, Vol. 132, Issue 4, pp. 617-33, (1996) (PubMed).
Aliases for Dynamitin 抗体
dynactin subunit 2 (DCTN2) 抗体dynactin subunit 2 S homeolog (dctn2.S) 抗体
Dynactin 2, p50 subunit (DCTN2-p50) 抗体
dynactin subunit 2 (dctn2) 抗体
dynactin 2 (Dctn2) 抗体
dynactin subunit 2 (Dctn2) 抗体
dynactin 2 (p50) (dctn2) 抗体
dynactin subunit 2 L homeolog (dctn2.L) 抗体
2310042E05Rik 抗体
C87049 抗体
C130077D06Rik 抗体
CG8269 抗体
DCTN-50 抗体
DCTN2 抗体
dctn2 抗体
dctn50 抗体
DCTN50 抗体
dDyn 抗体
Dmel\\CG8269 抗体
DMN 抗体
dmn 抗体
dyna 抗体
dynamitin 抗体
DYNAMITIN 抗体
GMP23-48K 抗体
l(2)k16109 抗体
l(2)k16218 抗体
P50 抗体
p50 抗体
p50/Dmn 抗体
p50/dynamitin 抗体
rbp50 抗体
RBP50 抗体
zgc:63867 抗体
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