DUSP7 产品
(Dual Specificity Phosphatase 7 (DUSP7))
Categories
Dual-specificity phosphatases (DUSPs) constitute a large heterogeneous subgroup of the type I cysteine-based protein-tyrosine phosphatase superfamily. DUSPs are characterized by their ability to dephosphorylate both tyrosine and serine/threonine residues. DUSP7 belongs to a class of DUSPs, designated MKPs, that dephosphorylate MAPK (mitogen-activated protein kinase) proteins ERK (see MIM 601795), JNK (see MIM 601158), and p38 (see MIM 600289) with specificity distinct from that of individual MKP proteins. MKPs contain a highly conserved C-terminal catalytic domain and an N-terminal Cdc25 (see MIM 116947)-like (CH2) domain. MAPK activation cascades mediate various physiologic processes, including cellular proliferation, apoptosis, differentiation, and stress responses (summary by Patterson et al., 2009 [PubMed 19228121]).[supplied by OMIM, Dec 2009].
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Featured DUSP7 Categories
Recommended DUSP7 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IHC, ELISA
Validations
- (3)
Cat. No.
ABIN7150785
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC (p)
Validations
- (3)
- (2)
Cat. No.
ABIN545058
Quantity
400 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC (p), ICC, IF
Validations
- (3)
Cat. No.
ABIN2856666
Quantity
100 μL
Datasheet
Datasheet
Recommended DUSP7 蛋白
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1352142
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
- (1)
Cat. No.
ABIN3079078
Quantity
1 mg
Datasheet
Datasheet
Reactivity
Mouse
Source
Tobacco (Nicotiana tabacum)
Validations
- (1)
Cat. No.
ABIN3127538
Quantity
1 mg
Datasheet
Datasheet
Latest Publications for our DUSP7 Products
: "MYC/MAX control ERK signaling and pluripotency by regulation of dual-specificity phosphatases 2 and 7." in: Genes & development, Vol. 27, Issue 7, pp. 725-33, (2013) (PubMed).: "Does the dual-specificity MAPK phosphatase Pyst2-L lead a monogamous relationship with the Erk2 protein?" in: Immunology letters, Vol. 92, Issue 1-2, pp. 149-56, (2004) (PubMed).
: "Dual-specificity phosphatase Pyst2-L is constitutively highly expressed in myeloid leukemia and other malignant cells." in: Oncogene, Vol. 22, Issue 48, pp. 7649-60, (2003) (PubMed).
: "cDNA microarray analysis reveals an overexpression of the dual-specificity MAPK phosphatase PYST2 in acute leukemia." in: Methods in enzymology, Vol. 366, pp. 103-13, (2003) (PubMed).
Synonyms and alternative names related to DUSP7
dual specificity phosphatase 7 (DUSP7), dual specificity phosphatase 7 (dusp7), Dual specificity protein phosphatase 7 (dus7), dual specificity phosphatase 7 (Dusp7), AU015694, DUSP7, mkp-x, mkp-X, mkpx, MKPX, Mkpx, pyst2, PYST2, Pyst2Protein level used designations for DUSP7
- dual specificity phosphatase 7
- dual specificity protein phosphatase 7-like
- Dual specificity protein phosphatase 7
- dual specificity protein phosphatase 7
- dual specificity protein phosphatase PYST2
- dual-specificity phosphatase-7
- MAP kinase phosphatase
- dual specificity protein phosphatase MKP-X
- hypothetical protein
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