DUSP2 产品
(Dual Specificity Phosphatase 2 (DUSP2))
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The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which are associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product inactivates ERK1 and ERK2, is predominantly expressed in hematopoietic tissues, and is localized in the nucleus. [provided by RefSeq, Jul 2008].
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Featured DUSP2 Categories
DUSP2 抗体
High quality antibodies with extensive validation data.
DUSP2 ELISA试剂盒
Reliable ELISA kits for a wide range of species.
Recommended DUSP2 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC
Validations
- (3)
Cat. No.
ABIN7190518
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB
Validations
- (1)
Cat. No.
ABIN7266847
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse
Application
WB, FACS
Validations
- (2)
Cat. No.
ABIN653027
Quantity
400 μL
Datasheet
Datasheet
Recommended DUSP2 ELISA试剂盒
Recommended DUSP2 蛋白
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
- (1)
Cat. No.
ABIN3079280
Quantity
1 mg
Datasheet
Datasheet
Reactivity
Mouse
Source
Tobacco (Nicotiana tabacum)
Validations
- (1)
Cat. No.
ABIN3121449
Quantity
1 mg
Datasheet
Datasheet
Latest Publications for our DUSP2 Products
: "Co-inhibition of NF-κB and JNK is synergistic in TNF-expressing human AML." in: The Journal of experimental medicine, Vol. 211, Issue 6, pp. 1093-108, (2014) (PubMed).: "MYC/MAX control ERK signaling and pluripotency by regulation of dual-specificity phosphatases 2 and 7." in: Genes & development, Vol. 27, Issue 7, pp. 725-33, (2013) (PubMed).
Synonyms and alternative names related to DUSP2
dual specificity phosphatase 2 (dusp2), dual specificity phosphatase 2 (DUSP2), dual specificity phosphatase 2 (Dusp2), PAC-1, PAC1, wu:fj40g04, zgc:91929Protein level used designations for DUSP2
- dual specificity protein phosphatase 2
- dual specificity protein phosphatase PAC-1
- dual-specificity phosphatase 2
- serine/threonine specific protein phosphatase
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