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Doublecortin 抗体

(Doublecortin (DCX))
This gene encodes a member of the doublecortin family. The protein encoded by this gene is a cytoplasmic protein and contains two doublecortin domains, which bind microtubules. In the developing cortex, cortical neurons must migrate over long distances to reach the site of their final differentiation. The encoded protein appears to direct neuronal migration by regulating the organization and stability of microtubules. In addition, the encoded protein interacts with LIS1, the regulatory gamma subunit of platelet activating factor acetylhydrolase, and this interaction is important to proper microtubule function in the developing cortex. Mutations in this gene cause abnormal migration of neurons during development and disrupt the layering of the cortex, leading to epilepsy, mental retardation, subcortical band heterotopia ('double cortex' syndrome) in females and lissencephaly ('smooth brain' syndrome) in males. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2010].

114 results

DCX 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
Pubmed 1 reference
产品编号 ABIN4886559
 
DCX 适用: 人, 小鼠, 大鼠, Cow, Pig, 哺乳动物 WB, IHC, IF, ICC 宿主: 小鼠 Monoclonal 3E1 unconjugated
产品编号 ABIN1580415
 
DCX 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB15193 unconjugated
产品编号 ABIN389254
 
DCX 适用: 人, 小鼠, 大鼠, Cow, 马, 犬, 兔, 豚鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2776750
 
DCX 适用: 人 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN357927
 
DCX 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p), FACS, IF (p), IHC (fro), IF (cc) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN684313
 
DCX 适用: 人, 小鼠, 大鼠 WB, FACS 宿主: 兔 Monoclonal 7C4 unconjugated
产品编号 ABIN6943114
 
DCX 适用: 人, 小鼠, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal Biotin
产品编号 ABIN674186
 
DCX 适用: 人, 小鼠, 大鼠 WB, IF (p) 宿主: 兔 Polyclonal AbBy Fluor® 594
产品编号 ABIN2812496
 
DCX 适用: 人, 小鼠, 大鼠 WB, IF (p) 宿主: 兔 Polyclonal AbBy Fluor® 350
产品编号 ABIN894287
 
DCX 适用: 人, 小鼠, 大鼠 WB, IF (p) 宿主: 兔 Polyclonal AbBy Fluor® 647
产品编号 ABIN894283
 
DCX 适用: 人, 小鼠, 大鼠 WB, IF (p) 宿主: 兔 Polyclonal AbBy Fluor® 555
产品编号 ABIN894286
 
DCX 适用: 人, 小鼠, 大鼠 WB, IF (p) 宿主: 兔 Polyclonal AbBy Fluor® 488
产品编号 ABIN894285
 
DCX 适用: 人, 小鼠, 大鼠 WB, IF (p) 宿主: 兔 Polyclonal Cy3
产品编号 ABIN674187
 
DCX 适用: 人, 小鼠, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal HRP
产品编号 ABIN674193
 
DCX 适用: 人, 小鼠, 大鼠 WB, IF (p) 宿主: 兔 Polyclonal FITC
产品编号 ABIN674191
 
DCX 适用: 人, 小鼠, 大鼠 WB, IF (p) 宿主: 兔 Polyclonal Cy5.5
产品编号 ABIN674189
 
DCX 适用: 人, 小鼠, 大鼠 WB, IF (p) 宿主: 兔 Polyclonal Cy7
产品编号 ABIN674190
 
DCX 适用: 人, 小鼠, 大鼠 WB, IF (p) 宿主: 兔 Polyclonal Cy5
产品编号 ABIN674188
 
DCX 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7181029
 
  • 类型 Primary
    • Primary
  • 应用范围
    • Western Blotting (WB)
    • ELISA
    • Immunohistochemistry (IHC)
    • Immunocytochemistry (ICC)
    • Immunofluorescence (IF)
    • Immunoprecipitation (IP)
    • Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    • Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    • Flow Cytometry (FACS)
    • Immunofluorescence (fixed cells) (IF/ICC)
    • Immunohistochemistry (Frozen Sections) (IHC (fro))
    • Fluorescence Microscopy (FM)
    • Enzyme Immunoassay (EIA)
    • Immunochromatography (IC)
    • Immunofluorescence (Cultured Cells) (IF (cc))
  • 适用
    • Human
    • Mouse
    • Rat
    • Horse
    • Cow
    • Pig
    • Chicken
    • Dog
    • Monkey
    • Drosophila melanogaster
    • Guinea Pig
    • Mammalian
    • Primate
    • Rabbit
  • 论文引用
  • 图像
  • Preservative free only
  • Carrier free only
  • 抗体来源
    • Rabbit
    • Mouse
    • Goat
    • Chicken
  • 克隆形成能力
    • Polyclonal
    • Monoclonal
  • 克隆
    • 3E1
    • 13B218
    • 1G12
    • 2G5
    • 3 e1
    • 4A3
    • 7C4
    • AOAD-4
    • BLR168J
    • RB15193
  • 抗原表位
    • Ser128
    • AA 1-441
    • AA 108-360
    • C-Term
    • pSer376
    • AA 1-360
    • AA 362-411
    • phosphorylated
    • AA 1-366
    • AA 107-137
    • AA 320-400
    • AA 346-395
    • AA 74-100
    • N-Term
    • Ser30
    • Ser376
    • AA 11-360
    • AA 154-411
    • AA 178-276
    • AA 180-260
    • AA 200-250
    • AA 206-255
    • AA 232-242
    • AA 254-303
    • AA 413-417
    • AA 69-81
    • AA 79-106
    • Lys292
    • Ser297
    • Ser378
    • pSer335
    • pSer47
  • 标记
    • 非结合性
    • Biotin
    • FITC
    • HRP
    • Alexa Fluor 488
    • Alexa Fluor 555
    • Alexa Fluor 594
    • Alexa Fluor 647
    • Alexa Fluor 680
    • Alexa Fluor 750
    • APC
    • AbBy Fluor® 350
    • AbBy Fluor® 488
    • AbBy Fluor® 555
    • AbBy Fluor® 594
    • AbBy Fluor® 647
    • Cy3
    • Cy5
    • Cy5.5
    • Cy7
    • PE
  • 抗体亚型
    • IgG
    • IgG1
    • Ig Fraction
    • IgG2a
  • 蛋白类型
    • Recombinant Antibody
  • Format
    • Liquid
    • Lyophilized
  • Grade
    • Verified
  • Supplier
    • antibodies-online
    • Signalway
    • Abbexa
    • Assay Biotechnology Company, Inc.
    • Biomatik
    • FabGennix
    • Rockland
    • Acris
    • Aviva Systems Biology
    • Boster Bio
    • NSJ Bioreagents
    • ProSci
    • Abcepta
    • Abiocode
    • EnCor Biotechnology
    • Neuromics Antibodies
    • USBio

Latest Publications for our Doublecortin 抗体

Zhang, Zhao, Zhang, Xu, Lian, Wu, He, Sun, Li: "Regulation of the p75 neurotrophin receptor attenuates neuroinflammation and stimulates hippocampal neurogenesis in experimental Streptococcus pneumoniae meningitis." in: Journal of neuroinflammation, Vol. 18, Issue 1, pp. 253, (2022) (PubMed).

Jiang, Brackeva, Stangé, Verhaeghen, Costa, Couillard-Després, Rotheneichner, Aigner, Van Schravendijk, Pipeleers, Ling, Gorus, Martens: "LC-MS/MS identification of doublecortin as abundant beta cell-selective protein discharged by damaged beta cells in vitro." in: Journal of proteomics, Vol. 80, pp. 268-80, (2013) (PubMed).

Klempin, Kronenberg, Cheung, Kettenmann, Kempermann: "Properties of doublecortin-(DCX)-expressing cells in the piriform cortex compared to the neurogenic dentate gyrus of adult mice." in: PLoS ONE, Vol. 6, Issue 10, pp. e25760, (2011) (PubMed).

Zhang, Du, Yang, Wang, Yu, Huang, Hu, Liu, Fu: "Granulocyte colony-stimulating factor increases the therapeutic efficacy of bone marrow mononuclear cell transplantation in cerebral ischemia in mice." in: BMC neuroscience, Vol. 12, pp. 61, (2011) (PubMed).

Evangelisti, Florian, Massimi, Dominici, Giannini, Galardi, Buè, Massalini, McDowell, Messi, Gulino, Farace, Ciafrè: "MiR-128 up-regulation inhibits Reelin and DCX expression and reduces neuroblastoma cell motility and invasiveness." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 23, Issue 12, pp. 4276-87, (2009) (PubMed).

Leger, Souville, Boddaert, Elie, Pinard, Plouin, Moutard, des Portes, Van Esch, Joriot, Renard, Chelly, Francis, Beldjord, Bahi-Buisson: "The location of DCX mutations predicts malformation severity in X-linked lissencephaly." in: Neurogenetics, Vol. 9, Issue 4, pp. 277-85, (2008) (PubMed).

Zhang, Ryan, Di Cesare, Liu, Walsh, You: "Doublecortin is expressed in articular chondrocytes." in: Biochemical and biophysical research communications, Vol. 363, Issue 3, pp. 694-700, (2007) (PubMed).

Magavi, Leavitt, Macklis: "Induction of neurogenesis in the neocortex of adult mice." in: Nature, Vol. 405, Issue 6789, pp. 951-5, (2000) (PubMed).

des Portes, Pinard, Billuart, Vinet, Koulakoff, Carrié, Gelot, Dupuis, Motte, Berwald-Netter, Catala, Kahn, Beldjord, Chelly: "A novel CNS gene required for neuronal migration and involved in X-linked subcortical laminar heterotopia and lissencephaly syndrome." in: Cell, Vol. 92, Issue 1, pp. 51-61, (1998) (PubMed).

Gleeson, Allen, Fox, Lamperti, Berkovic, Scheffer, Cooper, Dobyns, Minnerath, Ross, Walsh: "Doublecortin, a brain-specific gene mutated in human X-linked lissencephaly and double cortex syndrome, encodes a putative signaling protein." in: Cell, Vol. 92, Issue 1, pp. 63-72, (1998) (PubMed).

Aliases for Doublecortin 抗体

doublecortin (DCX) 抗体
doublecortin (Dcx) 抗体
18C15.5 抗体
DBCN 抗体
Dbct 抗体
DC 抗体
DCX 抗体
LISX 抗体
SCLH 抗体
XLIS 抗体
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