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DOT1L 抗体

(DOT1-Like, Histone H3 Methyltransferase (S. Cerevisiae) (DOT1L))
The protein encoded by this gene is a histone methyltransferase that methylates lysine-79 of histone H3. It is inactive against free core histones, but shows significant histone methyltransferase activity against nucleosomes. [provided by RefSeq, Aug 2011].
DOT1L 抗体  (AA 3-108) DOT1L 抗体  (AA 3-108) DOT1L 抗体 (AA 3-108) (ABIN566567)

DOT1L 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 6A6 unconjugated

DOT1L 抗体  (AA 331-484) DOT1L 抗体  (AA 331-484) DOT1L 抗体 (AA 331-484) (ABIN7155530)

DOT1L 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated

DOT1L 抗体  (C-Term) DOT1L 抗体  (C-Term) DOT1L 抗体 (C-Term) (ABIN6243177)

DOT1L 适用: 人 IHC (p) 宿主: 兔 Polyclonal RB2773 unconjugated

DOT1L 抗体 by 适用

Find DOT1L 抗体 for a variety of species such as anti-Human DOT1L, anti-Mouse DOT1L, anti-Rat DOT1L. The species listed below are among those available. Click on a link to go to the corresponding products.

DOT1L 抗体 by 应用范围

Find DOT1L 抗体 validated for a specific application such as WB, ELISA, IHC, IF (cc). Some of the available applications are listed below. Click on a link to go to the corresponding products.

DOT1L 抗体 by 抗体来源

Find DOT1L 抗体 with a specific 抗体来源. The 抗体来源 listed below are among those available. Click on a link to go to the corresponding products.

DOT1L 抗体 by 抗原表位

Find DOT1L 抗体 with a specific epitope. The epitopes listed below are among those available. Click on a link to go to the corresponding products.

DOT1L 抗体 by 克隆形成能力

Find available monoclonal or polyclonal DOT1L 抗体. Click on a link to go to the corresponding products.

DOT1L 抗体 by 克隆

Find DOT1L 抗体 with a specific 克隆. The 克隆 listed below are among those available. Click on a link to go to the corresponding products.

DOT1L 抗体 by 标记

Find DOT1L 抗体 with a specific conjugate such as FITC, Biotin, HRP. The conjugates listed below are among those available. Click on a link to go to the corresponding products.

Popular DOT1L 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, ELISA, IF
Validations
  • (1)
  • (4)
Cat. No. ABIN566567
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC
Validations
  • (3)
Cat. No. ABIN7155530
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application IHC (p)
Validations
  • (2)
  • (1)
Cat. No. ABIN6243177
Quantity 400 μL
Datasheet Datasheet
Reactivity Green Monkey, Human, Mouse, Rat
Application WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro), ICC
Validations
  • (1)
Cat. No. ABIN2690105
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (1)
Cat. No. ABIN7127593
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (1)
Cat. No. ABIN566566
Quantity 50 μL
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (1)
Cat. No. ABIN6971602
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, ELISA
Validations
  • (1)
Cat. No. ABIN6258125
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (1)
Cat. No. ABIN6139776
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (1)
Cat. No. ABIN6139773
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application ELISA, IHC
Validations
  • (2)
Cat. No. ABIN3028622
Quantity 0.4 mL
Datasheet Datasheet
Reactivity Green Monkey, Human, Mouse, Rat
Application WB, ELISA, IHC (p), IHC (fro)
Validations
Cat. No. ABIN2690106
Quantity 100 μL
Datasheet Datasheet
Reactivity Green Monkey, Human, Mouse, Rat
Application WB, IF (cc), IF (p)
Validations
Cat. No. ABIN6976627
Quantity 100 μL
Datasheet Datasheet
Reactivity Green Monkey, Human, Mouse, Rat
Application WB, IF (cc), IF (p)
Validations
Cat. No. ABIN6977488
Quantity 100 μL
Datasheet Datasheet
Reactivity Green Monkey, Human, Mouse, Rat
Application WB, IF (cc), IF (p)
Validations
Cat. No. ABIN6978349
Quantity 100 μL
Datasheet Datasheet

Latest Publications for our DOT1L 抗体

Lv, Li, Chen, Zhang, Tao, Tang, Wang, Che, Yu, He: "miR-133b suppresses colorectal cancer cell stemness and chemoresistance by targeting methyltransferase DOT1L." in: Experimental cell research, Vol. 385, Issue 1, pp. 111597, (2019) (PubMed).

Szablewski, Bret, Kassambara, Devin, Cartron, Costes-Martineau, Moreaux: "An epigenetic regulator-related score (EpiScore) predicts survival in patients with diffuse large B cell lymphoma and identifies patients who may benefit from epigenetic therapy." in: Oncotarget, Vol. 9, Issue 27, pp. 19079-19099, (2018) (PubMed).

Lakhdar, Drost, MacNee, Bastos, Rabinovich: "2D-DIGE proteomic analysis of vastus lateralis from COPD patients with low and normal fat free mass index and healthy controls." in: Respiratory research, Vol. 18, Issue 1, pp. 81, (2018) (PubMed).

Loeser, Waldschmidt, Kuetting, Heydt, Zander, Plum, Alakus, Buettner, Quaas: "Copy-number variation and protein expression of DOT1L in pancreatic adenocarcinoma as a potential drug target." in: Molecular and clinical oncology, Vol. 6, Issue 5, pp. 639-642, (2017) (PubMed).

Gilan, Lam, Becher, Lugo, Cannizzaro, Joberty, Ward, Wiese, Fong, Ftouni, Tyler, Stanley, MacPherson, Weng, Chan, Ghisi, Smil, Carpenter, Brown, Garton, Blewitt, Bannister, Kouzarides, Huntly et al.: "Functional interdependence of BRD4 and DOT1L in MLL leukemia. ..." in: Nature structural & molecular biology, Vol. 23, Issue 7, pp. 673-81, (2016) (PubMed).

Phillips, Wildt, Comizzoli: "Incidence of methylated histones H3K4 and H3K79 in cat germinal vesicles is regulated by specific nuclear factors at the acquisition of developmental competence during the folliculogenesis." in: Journal of assisted reproduction and genetics, Vol. 33, Issue 6, pp. 783-94, (2016) (PubMed).

Oksenych, Zhovmer, Ziani, Mari, Eberova, Nardo, Stefanini, Giglia-Mari, Egly, Coin: "Histone methyltransferase DOT1L drives recovery of gene expression after a genotoxic attack." in: PLoS genetics, Vol. 9, Issue 7, pp. e1003611, (2013) (PubMed).

Vernimmen, Lynch, De Gobbi, Garrick, Sharpe, Sloane-Stanley, Smith, Higgs: "Polycomb eviction as a new distant enhancer function." in: Genes & development, Vol. 25, Issue 15, pp. 1583-8, (2011) (PubMed).

Shah, Henriksen: "A novel disrupter of telomere silencing 1-like (DOT1L) interaction is required for signal transducer and activator of transcription 1 (STAT1)-activated gene expression." in: The Journal of biological chemistry, Vol. 286, Issue 48, pp. 41195-204, (2011) (PubMed).

Nguyen, Xiao, Neppl, Kallin, Li, Chen, Wang, Xiao, Zhang: "DOT1L regulates dystrophin expression and is critical for cardiac function." in: Genes & development, Vol. 25, Issue 3, pp. 263-74, (2011) (PubMed).

Aliases for DOT1L 抗体

histone-lysine N-methyltransferase, H3 lysine-79 specific (LOC100116648) 抗体
DOT1 like histone lysine methyltransferase (DOT1L) 抗体
histone methyltransferase (DOT1) 抗体
DOT1 like histone lysine methyltransferase (Dot1l) 抗体
DOT1-like, histone H3 methyltransferase (S. cerevisiae) (Dot1l) 抗体
A630076O07 抗体
AW907654 抗体
DOT1 抗体
Dot1 抗体
DOT1L 抗体
KMT4 抗体
mDot1 抗体
NV11307 抗体
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