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- 抗原 See all DOT1L 抗体
- DOT1L (DOT1-Like, Histone H3 Methyltransferase (S. Cerevisiae) (DOT1L))
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抗原表位
- C-Term
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This DOT1L antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 产品特性
- DOT1L (Disruptor of Telomeric silencing 1-like, also known as KMT4) is the mammalian homologue of the yeast Dot1 protein and the Drosophila Grappa protein. DOTL1 is the enzyme responsible for lysine 79 methylation of histone H3. DOT1L can promote an oncogenic pattern of gene expression through binding with several MLL fusion partners found in acute leukemia, thus leading to aberrant methylation of lysine 79 at MLL target genes. In contrast to most other histone lysine methyltransferases, DOT1L does not contain a SET domain. Biochemical studies suggest that recombinant DOT1L is active on recombinant nucleosomes. DOT1L antibody (pAb) was raised in a Rabbit host. It has been validated for use in Western blot, it has been shown to react with Human samples.
- 纯化方法
- Affinity Purified
- 免疫原
- This DOT1L antibody was raised against a peptide derived from the C-terminal region of human DOT1L.
- 亚型
- IgG
- Top Product
- Discover our top product DOT1L Primary Antibody
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anti-DOT1-Like, Histone H3 Methyltransferase (S. Cerevisiae) (DOT1L) (AA 3-108) antibody
DOT1L 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 6A6 unconjugated
anti-DOT1-Like, Histone H3 Methyltransferase (S. Cerevisiae) (DOT1L) (AA 331-484) antibodyDOT1L 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-DOT1-Like, Histone H3 Methyltransferase (S. Cerevisiae) (DOT1L) (AA 1390-1420), (C-Term) antibodyDOT1L 适用: 人 IHC (p) 宿主: 兔 Polyclonal RB2773 unconjugated
anti-DOT1-Like, Histone H3 Methyltransferase (S. Cerevisiae) (DOT1L) (AA 51-150) antibodyDOT1L 适用: 人, 小鼠, 大鼠, Green Monkey WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro), ICC 宿主: 兔 Polyclonal unconjugated
anti-DOT1-Like, Histone H3 Methyltransferase (S. Cerevisiae) (DOT1L) antibodyDOT1L 适用: 人 WB, ELISA 宿主: 兔 Monoclonal 3B6 unconjugated Recombinant Antibody
anti-DOT1-Like, Histone H3 Methyltransferase (S. Cerevisiae) (DOT1L) (AA 3-108) antibodyDOT1L 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-DOT1-Like, Histone H3 Methyltransferase (S. Cerevisiae) (DOT1L) (C-Term) antibodyDOT1L 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-DOT1-Like, Histone H3 Methyltransferase (S. Cerevisiae) (DOT1L) (AA 250-500) antibodyDOT1L 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-DOT1-Like, Histone H3 Methyltransferase (S. Cerevisiae) (DOT1L) (AA 1-250) antibodyDOT1L 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-DOT1-Like, Histone H3 Methyltransferase (S. Cerevisiae) (DOT1L) (AA 1390-1420) antibodyDOT1L 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 缓冲液
- Purified IgG in 70 mM Tris ( pH 8), 105 mM NaCl, 31 mM glycine, 0.07 mM EDTA, 30 % glycerol and 0.035 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.
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- 抗原
- DOT1L (DOT1-Like, Histone H3 Methyltransferase (S. Cerevisiae) (DOT1L))
- 别名
- DOT1L (DOT1L 产品)
- 别名
- NV11307 antibody, DOT1L antibody, DOT1 antibody, KMT4 antibody, A630076O07 antibody, AW907654 antibody, Dot1 antibody, mDot1 antibody, histone-lysine N-methyltransferase, H3 lysine-79 specific antibody, DOT1 like histone lysine methyltransferase antibody, histone methyltransferase antibody, DOT1-like, histone H3 methyltransferase (S. cerevisiae) antibody, LOC100116648 antibody, DOT1L antibody, DOT1 antibody, Dot1l antibody
- 分子量
- 200 kDa
- NCBI登录号
- NP_115871
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