Doublecortin 抗体 (C-Term)
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- 抗原 See all Doublecortin (DCX) 抗体
- Doublecortin (DCX)
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抗原表位
- C-Term
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适用
- 人, 小鼠, 大鼠, Cow, 犬, 马, 兔, 豚鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This Doublecortin antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC)
- 序列
- PEKFRYAQDD FSLDENECRV MKGNPSATAG PKASPTPQKT SAKSPGPMRR
- 预测反应
- Cow: 93%, Dog: 93%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%
- 产品特性
- This is a rabbit polyclonal antibody against DCX. It was validated on Western Blot using a cell lysate as a positive control.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the C terminal region of human DCX
- Top Product
- Discover our top product DCX Primary Antibody
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anti-Doublecortin (DCX) (AA 362-411) antibody
DCX 适用: 人 WB, ELISA, IHC, ICC, FACS 宿主: 小鼠 Monoclonal 2G5 unconjugated
anti-Doublecortin (DCX) (AA 232-242) antibodyVerified DCX 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF 宿主: 山羊 Polyclonal unconjugated
anti-Doublecortin (DCX) (AA 362-411) antibodyDCX 适用: 人 WB, ELISA, IHC, FACS, IF/ICC 宿主: 小鼠 Monoclonal unconjugated
anti-Doublecortin (DCX) (AA 1-360) antibodyDCX 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 1G12 unconjugated
anti-Doublecortin (DCX) (AA 69-81) antibodyVerified DCX 适用: 人 ELISA, IHC, IF, FACS 宿主: 山羊 Polyclonal unconjugated
anti-Doublecortin (DCX) (AA 108-360) antibodyDCX 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Doublecortin (DCX) antibodyDCX 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Doublecortin (DCX) (AA 11-360) antibodyDCX 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Doublecortin (DCX) antibodyDCX 适用: 小鼠, 大鼠 IHC 宿主: 兔 Polyclonal unconjugated
anti-Doublecortin (DCX) (Ser30) antibodyDCX 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 365 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- 抗原
- Doublecortin (DCX)
- 别名
- DCX (DCX 产品)
- 别名
- DCX antibody, DBCN antibody, DC antibody, LISX antibody, SCLH antibody, XLIS antibody, Dbct antibody, 18C15.5 antibody, doublecortin antibody, DCX antibody, Dcx antibody
- 背景
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In the developing cortex, cortical neurons must migrate over long distances to reach the site of their final differentiation. DCX is a cytoplasmic protein which appears to direct neuronal migration by regulating the organization and stability of microtubules. The protein contains two doublecortin domains, which bind microtubules. In addition, DCX interacts with LIS1, the regulatory gamma subunit of platelet activating factor acetylhydrolase, and this interaction is important to proper microtubule function in the developing cortex.In the developing cortex, cortical neurons must migrate over long distances to reach the site of their final differentiation. The protein encoded by this gene is a cytoplasmic protein which appears to direct neuronal migration by regulating the organization and stability of microtubules. The encoded protein contains two doublecortin domains, which bind microtubules. In addition, the encoded protein interacts with LIS1, the regulatory gamma subunit of platelet activating factor acetylhydrolase, and this interaction is important to proper microtubule function in the developing cortex. Mutations in this gene are a cause of X-linked lissencephaly. Multiple transcript variants encoding at least three different isoforms have been found for this gene.
Alias Symbols: DBCN, DC, LISX, SCLH, XLIS
Protein Interaction Partner: KIFC3, GOLGA2, TRIM23, KRTAP10-8, KRT40, RINT1, MID2, SPAG5, IKZF1, CALCOCO2, ZBTB5, TRIM27, MEOX1, FBXO25, APP, PPP1R9B, PPP1CA, PAFAH1B1, ACD, TINF2, POT1, TERF1, SPP1, USP9X, NFASC, TRIM39, AP1M1, AP2M1, DCX, CDK5,
Protein Size: 365 - 分子量
- 40 kDa
- 基因ID
- 1641
- NCBI登录号
- NM_178152, NP_835365
- UniProt
- O43602
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