DOK2 抗体
(DOK2)
The protein encoded by this gene is constitutively tyrosine phosphorylated in hematopoietic progenitors isolated from chronic myelogenous leukemia (CML) patients in the chronic phase. It may be a critical substrate for p210(bcr/abl), a chimeric protein whose presence is associated with CML. This encoded protein binds p120 (RasGAP) from CML cells. [provided by RefSeq, Jul 2008].
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Latest Publications for our DOK2 抗体
: "Dok-3 sequesters Grb2 and inhibits the Ras-Erk pathway downstream of protein-tyrosine kinases." in: Genes to cells : devoted to molecular & cellular mechanisms, Vol. 11, Issue 2, pp. 143-51, (2006) (PubMed).: "Profiling of tyrosine phosphorylation pathways in human cells using mass spectrometry." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 100, Issue 2, pp. 443-8, (2003) (PubMed).
: "Characterization of a novel member of the DOK family that binds and modulates Abl signaling." in: Molecular and cellular biology, Vol. 19, Issue 12, pp. 8314-25, (2000) (PubMed).
: "Coupling of Gab1 to c-Met, Grb2, and Shp2 mediates biological responses." in: The Journal of cell biology, Vol. 149, Issue 7, pp. 1419-32, (2000) (PubMed).
: "Molecular cloning and characterization of p56dok-2 defines a new family of RasGAP-binding proteins." in: The Journal of biological chemistry, Vol. 273, Issue 9, pp. 4827-30, (1998) (PubMed).
: "The Tek/Tie2 receptor signals through a novel Dok-related docking protein, Dok-R." in: Oncogene, Vol. 17, Issue 9, pp. 1097-108, (1998) (PubMed).
: "FRIP, a hematopoietic cell-specific rasGAP-interacting protein phosphorylated in response to cytokine stimulation." in: Immunity, Vol. 9, Issue 1, pp. 13-24, (1998) (PubMed).
Aliases for DOK2 抗体
docking protein 2 (DOK2) 抗体docking protein 2 (Dok2) 抗体
Dok-2 抗体
DokR 抗体
Frip 抗体
p56DOK 抗体
p56dok-2 抗体
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