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DOK2 抗体 (pTyr299)

The 兔 多克隆 anti-DOK2 antibody is suitable to detect DOK2 in samples from 人, 小鼠 和 猴. It has been validated for WB, ELISA 和 IF.
产品编号 ABIN1531817
发货至: 中国
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Quick Overview for DOK2 抗体 (pTyr299) (ABIN1531817)

抗原

See all DOK2 抗体
DOK2

适用

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人, 小鼠, 猴

宿主

  • 127
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兔

克隆类型

  • 127
  • 5
多克隆

标记

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This DOK2 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunofluorescence (IF)
  • 抗原表位

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    AA 266-315, pTyr299

    原理

    Dok-2 (phospho Tyr299) Antibody

    特异性

    Phospho-Dok-2 (Y299) Polyclonal Antibody detects endogenous levels of Dok-2 protein only when phosphorylated at Y299.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

    纯度

    > 95 %

    免疫原

    The antiserum was produced against synthesized peptide derived from human p56 Dok-2 around the phosphorylation site of Tyr299. AA range:266-315

    亚型

    IgG
  • 应用备注

    WB 1:500 - 1:2000. IF 1:200 - 1:1000. ELISA: 1:20000. Not yet tested in other applications.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C/1 year

    有效期

    12 months
  • 抗原

    DOK2

    别名

    p56 Dok-2

    背景

    Synonyms: DOK2, Docking protein 2, Downstream of tyrosine kinase 2, p56(dok-2)

    Background: docking protein 2(DOK2) Homo sapiens The protein encoded by this gene is constitutively tyrosine phosphorylated in hematopoietic progenitors isolated from chronic myelogenous leukemia (CML) patients in the chronic phase. It may be a critical substrate for p210(bcr/abl), a chimeric protein whose presence is associated with CML. This encoded protein binds p120 (RasGAP) from CML cells. [provided by RefSeq, Jul 2008],

    Gene Name: DOK2

    Protein Name: Docking protein 2

    分子量

    45 kDa

    基因ID

    9046

    OMIM

    604997

    UniProt

    O60496
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