DOK2 抗体 (pTyr299)
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Quick Overview for DOK2 抗体 (pTyr299) (ABIN1531817)
抗原
See all DOK2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 266-315, pTyr299
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原理
- Dok-2 (phospho Tyr299) Antibody
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特异性
- Phospho-Dok-2 (Y299) Polyclonal Antibody detects endogenous levels of Dok-2 protein only when phosphorylated at Y299.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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纯度
- > 95 %
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免疫原
- The antiserum was produced against synthesized peptide derived from human p56 Dok-2 around the phosphorylation site of Tyr299. AA range:266-315
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亚型
- IgG
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应用备注
- WB 1:500 - 1:2000. IF 1:200 - 1:1000. ELISA: 1:20000. Not yet tested in other applications.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- DOK2
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别名
- p56 Dok-2
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背景
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Synonyms: DOK2, Docking protein 2, Downstream of tyrosine kinase 2, p56(dok-2)
Background: docking protein 2(DOK2) Homo sapiens The protein encoded by this gene is constitutively tyrosine phosphorylated in hematopoietic progenitors isolated from chronic myelogenous leukemia (CML) patients in the chronic phase. It may be a critical substrate for p210(bcr/abl), a chimeric protein whose presence is associated with CML. This encoded protein binds p120 (RasGAP) from CML cells. [provided by RefSeq, Jul 2008],
Gene Name: DOK2
Protein Name: Docking protein 2
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分子量
- 45 kDa
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基因ID
- 9046
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OMIM
- 604997
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UniProt
- O60496
抗原
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