DNMT3A 抗体
(DNA (Cytosine-5-)-Methyltransferase 3 alpha (DNMT3A))
CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. This gene encodes a DNA methyltransferase that is thought to function in de novo methylation, rather than maintenance methylation. The protein localizes to the cytoplasm and nucleus and its expression is developmentally regulated. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008].
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152 results
DNMT3A
适用: 人, 小鼠
WB, IHC, ICC, ChIP
宿主: 小鼠
Monoclonal
64B1446
unconjugated
2 images
Latest Publications for our DNMT3A 抗体
: "Integrative Proteomic Profiling Reveals PRC2-Dependent Epigenetic Crosstalk Maintains Ground-State Pluripotency." in: Cell stem cell, Vol. 24, Issue 1, pp. 123-137.e8, (2019) (PubMed).: "Gain-of-function DNMT3A mutations cause microcephalic dwarfism and hypermethylation of Polycomb-regulated regions. ..." in: Nature genetics, Vol. 51, Issue 1, pp. 96-105, (2019) (PubMed).
: "Examining How the MAFB Transcription Factor Affects Islet β-Cell Function Postnatally." in: Diabetes, Vol. 68, Issue 2, pp. 337-348, (2019) (PubMed).
: "The triterpenoid corosolic acid blocks transformation and epigenetically reactivates Nrf2 in TRAMP-C1 prostate cells." in: Molecular carcinogenesis, (2018) (PubMed).
: "Identification of dynamic undifferentiated cell states within the male germline." in: Nature communications, Vol. 9, Issue 1, pp. 2819, (2018) (PubMed).
: "Imprinted and DNA methyltransferase gene expression in the endometrium during the pre- and peri-implantation period in cattle." in: Reproduction, fertility, and development, Vol. 29, Issue 9, pp. 1729-1738, (2018) (PubMed).
: "DNA Demethylation by DNMT3A and DNMT3B in vitro and of Methylated Episomal DNA in Transiently Transfected Cells." in: Biochimica et biophysica acta. Gene regulatory mechanisms, Vol. 1861, Issue 11, pp. 1048-1061, (2018) (PubMed).
: "MYC and DNMT3A-mediated DNA methylation represses microRNA-200b in triple negative breast cancer." in: Journal of cellular and molecular medicine, Vol. 22, Issue 12, pp. 6262-6274, (2018) (PubMed).
: "Intragenic DNA methylation prevents spurious transcription initiation." in: Nature, Vol. 543, Issue 7643, pp. 72-77, (2017) (PubMed).
: "Epigenetic determinants of space radiation-induced cognitive dysfunction." in: Scientific reports, Vol. 7, pp. 42885, (2017) (PubMed).
Aliases for DNMT3A 抗体
DNA methyltransferase 3 alpha (DNMT3A) 抗体DNA methyltransferase 3A (Dnmt3a) 抗体
DNA methyltransferase 3 alpha (Dnmt3a) 抗体
DNA methyltransferase 3 alpha (dnmt3a) 抗体
DNA (cytosine-5-)-methyltransferase 3 alpha b (dnmt3ab) 抗体
DNMT3A 抗体
dnmt3a1 抗体
DNMT3A2 抗体
dnmt6 抗体
M.HsaIIIA 抗体
MmuIIIA 抗体
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