DIS3L 抗体
(DIS3-Like Exonuclease 1 (DIS3L))
Putative cytoplasm-specific catalytic component of the RNA exosome complex which has 3'->5' exoribonuclease activity and participates in a multitude of cellular RNA processing and degradation events. In the cytoplasm, the RNA exosome complex is involved in general mRNA turnover and specifically degrades inherently unstable mRNAs containing AU-rich elements (AREs) within their 3' untranslated regions, and in RNA surveillance pathways, preventing translation of aberrant mRNAs. It seems to be involved in degradation of histone mRNA.
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Latest Publications for our DIS3L 抗体
: "Multiple myeloma-associated hDIS3 mutations cause perturbations in cellular RNA metabolism and suggest hDIS3 PIN domain as a potential drug target." in: Nucleic acids research, Vol. 42, Issue 2, pp. 1270-90, (2014) (PubMed).: "Dis3-like 1: a novel exoribonuclease associated with the human exosome." in: The EMBO journal, Vol. 29, Issue 14, pp. 2358-67, (2010) (PubMed).
Aliases for DIS3L 抗体
DIS3 like exosome 3'-5' exoribonuclease (DIS3L) 抗体DIS3 like exosome 3'-5' exoribonuclease (dis3l) 抗体
DIS3 like exosome 3'-5' exoribonuclease (Dis3l) 抗体
DIS3-like exosome 3'-5' exoribonuclease (Dis3l) 抗体
DIS3 like exosome 3'-5' exoribonuclease (dis3l.L) 抗体
AV340375 抗体
DIS3L1 抗体
RGD1308959 抗体
zgc:158615 抗体
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