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DAPK2 产品

(Death-Associated Protein Kinase 2 (DAPK2))

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This gene encodes a protein that belongs to the serine/threonine protein kinase family. This protein contains a N-terminal protein kinase domain followed by a conserved calmodulin-binding domain with significant similarity to that of death-associated protein kinase 1 (DAPK1), a positive regulator of programmed cell death. Overexpression of this gene was shown to induce cell apoptosis. It uses multiple polyadenylation sites. [provided by RefSeq, Jul 2008].

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Featured DAPK2 Categories

DAPK2 抗体

High quality antibodies with extensive validation data.

DAPK2 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended DAPK2 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, ELISA, IHC, IF
Validations
  • (5)
Cat. No. ABIN7149554
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (4)
Cat. No. ABIN565126
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, IF
Validations
  • (4)
Cat. No. ABIN6139403
Quantity 100 μL
Datasheet Datasheet

Recommended DAPK2 ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN6210405
Quantity 96 tests
Datasheet Datasheet

Recommended DAPK2 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1351100
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Insect Cells
Validations
Cat. No. ABIN5508889
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7421344
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our DAPK2 Products

Cai, Cao, Zhang, Xue, Zhang, Zhou, Zhou, Sun, Fu: "Oncogenic miR-17/20a Forms a Positive Feed-forward Loop with the p53 Kinase DAPK3 to Promote Tumorigenesis." in: The Journal of biological chemistry, Vol. 290, Issue 32, pp. 19967-75, (2015) (PubMed).

Geering, Stoeckle, Rozman, Oberson, Benarafa, Simon: "DAPK2 positively regulates motility of neutrophils and eosinophils in response to intermediary chemoattractants." in: Journal of leukocyte biology, Vol. 95, Issue 2, pp. 293-303, (2014) (PubMed).

Chen, Huang, Chu, Chen, Chou, Wang, Kulp, Teng, Wang, Chen: "Energy restriction-mimetic agents induce apoptosis in prostate cancer cells in part through epigenetic activation of KLF6 tumor suppressor gene expression." in: The Journal of biological chemistry, Vol. 286, Issue 12, pp. 9968-76, (2011) (PubMed).

Karur, Lowell, Besmer, Agosti, Wojchowski: "Lyn kinase promotes erythroblast expansion and late-stage development." in: Blood, Vol. 108, Issue 5, pp. 1524-32, (2006) (PubMed).

Satoh, Toyota, Itoh, Kikuchi, Obata, Sasaki, Suzuki, Yawata, Kusano, Fujita, Hosokawa, Yanagihara, Tokino, Imai: "DNA methylation and histone deacetylation associated with silencing DAP kinase gene expression in colorectal and gastric cancers." in: British journal of cancer, Vol. 86, Issue 11, pp. 1817-23, (2002) (PubMed).

Chan, Chan, Tang, Tong, Lo, Lee, Cheung, Wong, Chan, Lai, To: "Hypermethylation of multiple genes in tumor tissues and voided urine in urinary bladder cancer patients." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 8, Issue 2, pp. 464-70, (2002) (PubMed).

Wong, Chang, Tang, Wei, Kwong, Sham, Yuen, Kwong: "High frequency of promoter hypermethylation of the death-associated protein-kinase gene in nasopharyngeal carcinoma and its detection in the peripheral blood of patients." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 8, Issue 2, pp. 433-7, (2002) (PubMed).

Shani, Henis-Korenblit, Jona, Gileadi, Eisenstein, Ziv, Admon, Kimchi: "Autophosphorylation restrains the apoptotic activity of DRP-1 kinase by controlling dimerization and calmodulin binding." in: The EMBO journal, Vol. 20, Issue 5, pp. 1099-113, (2001) (PubMed).

Pazdernik, Donner, Goebl, Harrington: "Mouse receptor interacting protein 3 does not contain a caspase-recruiting or a death domain but induces apoptosis and activates NF-kappaB." in: Molecular and cellular biology, Vol. 19, Issue 10, pp. 6500-8, (2000) (PubMed).

Inbal, Shani, Cohen, Kissil, Kimchi: "Death-associated protein kinase-related protein 1, a novel serine/threonine kinase involved in apoptosis." in: Molecular and cellular biology, Vol. 20, Issue 3, pp. 1044-54, (2000) (PubMed).

Synonyms and alternative names related to DAPK2

death-associated protein kinase 2 L homeolog (dapk2.L), death associated protein kinase 2 (DAPK2), death-associated protein kinase 2b (dapk2b), death-associated protein kinase 2 (dapk2), death-associated protein kinase 2 (Dapk2), DAPK2, dapk2, drp-1, DRP-1, drp1, DRP1

Protein level used designations for DAPK2

  • death-associated protein kinase 2
  • DAP kinase 2
  • DAP-kinase-related protein 1 beta isoform
  • DRP-1
  • death-associated kinase 2
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