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DAZL 产品

(Deleted in Azoospermia-Like (DAZL))
The DAZ (Deleted in AZoospermia) gene family encodes potential RNA binding proteins that are expressed in prenatal and postnatal germ cells of males and females. The protein encoded by this gene is localized to the nucleus and cytoplasm of fetal germ cells and to the cytoplasm of developing oocytes. In the testis, this protein is localized to the nucleus of spermatogonia but relocates to the cytoplasm during meiosis where it persists in spermatids and spermatozoa. Transposition and amplification of this autosomal gene during primate evolution gave rise to the DAZ gene cluster on the Y chromosome. Mutations in this gene have been linked to severe spermatogenic failure and infertility in males. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2010].

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Featured DAZL Categories

DAZL 抗体

High quality antibodies with extensive validation data.

DAZL ELISA试剂盒

Reliable ELISA kits for a wide range of species.

DAZL 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended DAZL 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IHC, IF
Validations
  • (5)
Cat. No. ABIN6139416
Quantity 100 μL
Datasheet Datasheet
Reactivity Rat
Application WB, ELISA
Validations
  • (3)
Cat. No. ABIN185441
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application ELISA, IHC, IF
Validations
  • (2)
Cat. No. ABIN7149640
Quantity 100 μg
Datasheet Datasheet

Recommended DAZL ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method
Validations
Cat. No. ABIN1129363
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method
Validations
Cat. No. ABIN1129364
Quantity 96 tests
Datasheet Datasheet
Reactivity Chicken
Analytical Method
Validations
Cat. No. ABIN1129362
Quantity 96 tests
Datasheet Datasheet

Recommended DAZL 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1777509
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
Cat. No. ABIN3078670
Quantity 1 mg
Datasheet Datasheet
Reactivity Mouse
Source Tobacco (Nicotiana tabacum)
Validations
Cat. No. ABIN3123297
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our DAZL Products

Zhang, Zhao, Zhang, Hao, Yu, Min, Li, Ma, Chen, Yi, Tang, Meng, Liu, Wang, Shen, Zhang: "Decrease in male mouse fertility by hydrogen sulfide and/or ammonia can Be inheritable." in: Chemosphere, Vol. 194, pp. 147-157, (2018) (PubMed).

Fang, Angulo, Xia, Sukhwani, Wang, Carey, Mazurie, Cui, Wilkinson, Wiedenheft, Irie, Surani, Orwig, Reijo Pera: "A PAX5-OCT4-PRDM1 developmental switch specifies human primordial germ cells." in: Nature cell biology, Vol. 20, Issue 6, pp. 655-665, (2018) (PubMed).

Levi, Stemmer, Stein, Shalgi, Ben-Aharon: "Treosulfan induces distinctive gonadal toxicity compared with busulfan." in: Oncotarget, Vol. 9, Issue 27, pp. 19317-19327, (2018) (PubMed).

Liu, Cai, Jin, Peng, Pan, Zhang, Han, Xu, Lin: "Abnormal gametogenesis induced by p53 deficiency promotes tumor progression and drug resistance." in: Cell discovery, Vol. 4, pp. 54, (2018) (PubMed).

Guo, Li, Wang, He, Zheng: "Germ stem cells are active in postnatal mouse ovary under physiological conditions." in: Molecular human reproduction, Vol. 22, Issue 5, pp. 316-28, (2016) (PubMed).

Levi, Tzabari, Savion, Stemmer, Shalgi, Ben-Aharon: "Dexrazoxane exacerbates doxorubicin-induced testicular toxicity." in: Reproduction (Cambridge, England), Vol. 150, Issue 4, pp. 357-66, (2015) (PubMed).

Dominguez, Chiang, Sukhwani, Orwig, Reijo Pera: "Human germ cell formation in xenotransplants of induced pluripotent stem cells carrying X chromosome aneuploidies." in: Scientific reports, Vol. 4, pp. 6432, (2014) (PubMed).

Djureinovic, Fagerberg, Hallström, Danielsson, Lindskog, Uhlén, Pontén: "The human testis-specific proteome defined by transcriptomics and antibody-based profiling." in: Molecular human reproduction, Vol. 20, Issue 6, pp. 476-88, (2014) (PubMed).

Harkey, Asano, Zoulas, Torok-Storb, Nagashima, Travis: "Isolation, genetic manipulation, and transplantation of canine spermatogonial stem cells: progress toward transgenesis through the male germ-line." in: Reproduction (Cambridge, England), Vol. 146, Issue 1, pp. 75-90, (2013) (PubMed).

Barrios, Filipponi, Pellegrini, Paronetto, Di Siena, Geremia, Rossi, De Felici, Jannini, Dolci: "Opposing effects of retinoic acid and FGF9 on Nanos2 expression and meiotic entry of mouse germ cells." in: Journal of cell science, Vol. 123, Issue Pt 6, pp. 871-80, (2010) (PubMed).

Synonyms and alternative names related to DAZL

deleted in azoospermia like (DAZL), deleted in azoospermia-like (DAZL), deleted in azoospermia-like (dazl), deleted in azoospermia-like (Dazl), deleted in azoospermia-like L homeolog (dazl.L), deleted in azoospermia like (dazl), deleted in azoospermia like (Dazl), Daz-like, DAZH, dazh, Dazh, DAZL, dazl-a, dazl-B, DAZL1, dazl1, Dazl1, DAZLA, dazla, Dazla, SPGYLA, spgyla, Tpx-2, Tpx2, Xdazl

Protein level used designations for DAZL

  • DAZ homolog
  • DAZ-like autosomal
  • SPGY-like-autosomal
  • deleted in azoospermia-like 1
  • germline specific RNA binding protein
  • spermatogenesis gene on the Y-like autosomal
  • deleted in azoospermia-like
  • DAZ-like protein
  • deleted in azoospermia-like protein
  • deleted in azoospermia protein 3
  • xtdazl
  • DAZ-like protein A
  • DAZ-like protein B
  • Deleted in azoospermia-like-B
  • deleted in azoospermia-like-A
  • xDazl-A
  • xDazl-B
  • Deleted in azoospermia-like 1
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