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DAB1 产品

(Disabled Homolog 1 (Drosophila) (DAB1))

Categories

The laminar organization of multiple neuronal types in the cerebral cortex is required for normal cognitive function. In mice, the disabled-1 gene plays a central role in brain development, directing the migration of cortical neurons past previously formed neurons to reach their proper layer. This gene is similar to disabled-1, and the protein encoded by this gene is thought to be a signal transducer that interacts with protein kinase pathways to regulate neuronal positioning in the developing brain. Alternatively spliced transcript variants of this gene have been reported, but their full length nature has not been determined. [provided by RefSeq, Jul 2008].

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Featured DAB1 Categories

DAB1 抗体

High quality antibodies with extensive validation data.

DAB1 ELISA试剂盒

Reliable ELISA kits for a wide range of species.

DAB1 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended DAB1 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Mouse, Rat
Application WB, ELISA, IF, ICC
Validations
  • (1)
  • (3)
Cat. No. ABIN6256680
Quantity 100 μL
Datasheet Datasheet
Reactivity Mouse, Rabbit
Application WB, ELISA, IHC, IP
Validations
  • (1)
  • (3)
Cat. No. ABIN6658036
Quantity 25 μL
Datasheet Datasheet
Reactivity Mouse
Application WB, ELISA, IHC, IP
Validations
  • (6)
  • (3)
Cat. No. ABIN6657863
Quantity 100 μL
Datasheet Datasheet

Recommended DAB1 ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6966387
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6966386
Quantity 96 tests
Datasheet Datasheet
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6955408
Quantity 96 tests
Datasheet Datasheet

Recommended DAB1 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1351059
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3078708
Quantity 1 mg
Datasheet Datasheet
Reactivity Mouse
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3121140
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our DAB1 Products

Meseke, Neumüller, Brunne, Li, Anstötz, Pohlkamp, Rogalla, Herz, Rune, Bender: "Distal Dendritic Enrichment of HCN1 Channels in Hippocampal CA1 Is Promoted by Estrogen, but Does Not Require Reelin." in: eNeuro, Vol. 5, Issue 5, (2019) (PubMed).

Liu, Li, Shu, Xiao, Feng: "Ephrin‑b3 modulates hippocampal neurogenesis and the reelin signaling pathway in a pilocarpine‑induced model of epilepsy." in: International journal of molecular medicine, Vol. 41, Issue 6, pp. 3457-3467, (2018) (PubMed).

Fairchild, Hino, Han, Miltner, Peinado Allina, Brown, Burns, La Torre, Simó: "RBX2 maintains final retinal cell position in a DAB1-dependent and -independent fashion." in: Development (Cambridge, England), Vol. 145, Issue 3, (2018) (PubMed).

Su, Haner, Imbery, Brooks, Morhardt, Gorse, Guido, Fox: "Reelin is required for class-specific retinogeniculate targeting." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 31, Issue 2, pp. 575-86, (2011) (PubMed).

Katyal, Gao, Monckton, Glubrecht, Godbout: "Hierarchical disabled-1 tyrosine phosphorylation in Src family kinase activation and neurite formation." in: Journal of molecular biology, Vol. 368, Issue 2, pp. 349-64, (2007) (PubMed).

Chen, Ochalski, Tran, Sahir, Schubert, Pramatarova, Howell: "Interaction between Dab1 and CrkII is promoted by Reelin signaling." in: Journal of cell science, Vol. 117, Issue Pt 19, pp. 4527-36, (2004) (PubMed).

Strasser, Fasching, Hauser, Mayer, Bock, Hiesberger, Herz, Weeber, Sweatt, Pramatarova, Howell, Schneider, Nimpf: "Receptor clustering is involved in Reelin signaling." in: Molecular and cellular biology, Vol. 24, Issue 3, pp. 1378-86, (2004) (PubMed).

Bramblett, Pennesi, Wu, Tsai: "The transcription factor Bhlhb4 is required for rod bipolar cell maturation." in: Neuron, Vol. 43, Issue 6, pp. 779-93, (2004) (PubMed).

Kim, Qu, Kriho, Lacor, Smalheiser, Pappas, Guidotti, Costa, Sugaya: "Reelin function in neural stem cell biology." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 99, Issue 6, pp. 4020-5, (2002) (PubMed).

Keshvara, Magdaleno, Benhayon, Curran: "Cyclin-dependent kinase 5 phosphorylates disabled 1 independently of Reelin signaling." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 22, Issue 12, pp. 4869-77, (2002) (PubMed).

Synonyms and alternative names related to DAB1

DAB1, reelin adaptor protein (DAB1), disabled 1 (Dab1), DAB1, reelin adaptor protein (Dab1), disabled homolog 1 (LOC100232823), Dab, reelin signal transducer, homolog 1a (Drosophila) (dab1a), Dab, reelin signal transducer, homolog 1b (Drosophila) (dab1b), AI956902, C630028C02Rik, DAB1, disabled-1, LOC100232823, scm, scr, scrambler, si:dkey-242m13.1, yot, zgc:136547

Protein level used designations for DAB1

  • disabled homolog 1
  • yotari
  • disabled1
  • disabled homolog 1 (Drosophila)
  • DAB1 variant protein-like
  • disabled homolog 1-like
  • disabled 1 type B
  • disabled homolog 1b
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