(Cytochrome P450, Family 4, Subfamily F, Polypeptide 11 (CYP4F11))
This gene, CYP4F11, encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This gene is part of a cluster of cytochrome P450 genes on chromosome 19. Another member of this family, CYP4F2, is approximately 16 kb away. Alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008].
Kumarakulasingham, Rooney, Dundas, Telfer, Melvin, Curran, Murray: "Cytochrome p450 profile of colorectal cancer: identification of markers of prognosis." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 11, Issue 10, pp. 3758-65, (2005) (PubMed).
Kalsotra, Turman, Kikuta, Strobel: "Expression and characterization of human cytochrome P450 4F11: Putative role in the metabolism of therapeutic drugs and eicosanoids." in: Toxicology and applied pharmacology, Vol. 199, Issue 3, pp. 295-304, (2004) (PubMed).
Cui, Nelson, Strobel: "A novel human cytochrome P450 4F isoform (CYP4F11): cDNA cloning, expression, and genomic structural characterization." in: Genomics, Vol. 68, Issue 2, pp. 161-6, (2000) (PubMed).
Aliases for CYP4F11 抗体
cytochrome P450, family 4, subfamily F, polypeptide 11 (CYP4F11) 抗体 cytochrome P450 family 4 subfamily F member 11 (CYP4F11) 抗体 CYPIVF11 抗体