This gene encodes an essential structural component of the synaptonemal complex. This complex is involved in synapsis, recombination and segregation of meiotic chromosomes. Mutations in this gene are associated with azoospermia in males and susceptibility to pregnancy loss in females. Alternate splicing results in multiple transcript variants that encode the same protein. [provided by RefSeq, May 2010].
Kashuba, Li, Wang, Senchenko, Protopopov, Malyukova, Kutsenko, Kadyrova, Zabarovska, Muravenko, Zelenin, Kisselev, Kuzmin, Minna, Winberg, Ernberg, Braga, Lerman, Klein, Zabarovsky: "RBSP3 (HYA22) is a tumor suppressor gene implicated in major epithelial malignancies." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 101, Issue 14, pp. 4906-11, (2004) (PubMed).
Aliases for CTDSPL 抗体
CTD small phosphatase like (CTDSPL) 抗体 TIM23 translocase complex subunit Tim50 (SJAG_03560) 抗体 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like (Ctdspl) 抗体 CTD small phosphatase like (Ctdspl) 抗体 CTD small phosphatase like S homeolog (ctdspl.S) 抗体 2810418J22Rik 抗体 AI426263 抗体 C3orf8 抗体 ctdspl 抗体 ctdspl.L 抗体 HYA22 抗体 NFI1 抗体 NIF 抗体 nif 抗体 PSR1 抗体 RBSP3 抗体 SCP3 抗体 scp3 抗体 XNIF 抗体