The protein encoded by this gene is a cytokine that controls the production, differentiation, and function of macrophages. The active form of the protein is found extracellularly as a disulfide-linked homodimer, and is thought to be produced by proteolytic cleavage of membrane-bound precursors. The encoded protein may be involved in development of the placenta. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2011].
Latest Publications for our Colony Stimulating Factor 1 (Macrophage) 蛋白
Wang, Li, Shen, Liang, Li, Huang, Liu, Jiang, Yang, Zhao, Yang: "PDL1 Fusion Protein Protects Against Experimental Cerebral Malaria via Repressing Over-Reactive CD8+ T Cell Responses." in: Frontiers in immunology, Vol. 9, pp. 3157, (2019) (PubMed).
Li, Zeng, Xie, Yue, Deng, Ma, Zheng, Wu, Luo, Liu: "Inhibition of Osteoclastogenesis and Bone Resorption in vitro and in vivo by a prenylflavonoid xanthohumol from hops." in: Scientific reports, Vol. 5, pp. 17605, (2016) (PubMed).
Bertin, Barat, Bélanger, Tremblay: "Leukotrienes inhibit early stages of HIV-1 infection in monocyte-derived microglia-like cells." in: Journal of neuroinflammation, Vol. 9, pp. 55, (2012) (PubMed).
Del Galdo, Wermuth, Addya, Fortina, Jimenez et al.: "NF?B activation and stimulation of chemokine production in normal human macrophages by the gadolinium-based magnetic resonance contrast agent Omniscan: possible role in the pathogenesis of ..." in: Annals of the rheumatic diseases, Vol. 69, Issue 11, pp. 2024-33, (2010) (PubMed).
Aliases for Colony Stimulating Factor 1 (Macrophage) 蛋白